Characterizing the spectrum of right ventricular remodelling in response to chronic training
Por:
Sitges M, Merino B, Butakoff C, Sanz de la Garza M, Paré C, Montserrat S, Vidal B, Azqueta M, Sarquella-Brugada G, Gutierrez JA, Canal R, Brugada-Terradellas J and Bijnens BH
Publicada:
1 mar 2017
Resumen:
The significance and spectrum of reduced right ventricular (RV) deformation, reported in endurance athletes, is unclear. To comprehensively analyze the cardiac performance at rest of athletes, especially focusing on integrating RV size and deformation to unravel the underlying triggers of this ventricular remodelling. Hundred professional male athletes and 50 sedentary healthy males of similar age were prospectively studied. Conventional echocardiographic parameters of all four chambers were obtained, as well as 2D echo-derived strain (2DSE) in the left (LV) and in the RV free wall with separate additional analysis of the RV basal and apical segments. Left and right-sided dimensions were larger in athletes than in controls, but with a disproportionate RA enlargement. RV global strain was lower in sportsmen (-26.8 +/- 2.8% vs -28.5 +/- 3.4%, p < 0.001) due to a decrease in the basal segment (-22.8 +/- 3.5% vs -25.8 +/- 4.0%, p < 0.001) resulting in a marked gradient of deformation from the RV inlet towards the apex. By integrating size, deformation and stroke volume, we observed that the LV working conditions were similar in all sportsmen while a wider variability existed in the RV. Cardiac remodelling in athletes is more pronounced in the right heart cavities with specific regional differences within the right ventricle, but with a wide variability among individuals. The large inter-individual differences, as well as its acute and chronic relevance warrant further investigation.
Filiaciones:
Sitges M:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Merino B:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Butakoff C:
Universitat Pompeu Fabra, Barcelona, Spain
Sanz de la Garza M:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain.
Serveis Médics Futbol Club Barcelona, Barcelona, Spain.
Paré C:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Montserrat S:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Vidal B:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Azqueta M:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Sarquella-Brugada G:
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Gutierrez JA:
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Canal R:
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Brugada-Terradellas J:
Cardiology Department, Hospital Clínic, IDIBAPS: Institut de Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Villarroel 136, 08036, Barcelona, Spain
Serveis Médics Futbol Club Barcelona, Barcelona, Spain
Bijnens BH:
Universitat Pompeu Fabra, Barcelona, Spain
ICREA, Barcelona, Spain
Green Accepted
|