Placental Mitochondrial Toxicity, Oxidative Stress, Apoptosis, and Adverse Perinatal Outcomes in HIV Pregnancies Under Antiretroviral Treatment Containing Zidovudine.
Por:
Hernández S, Catalán-García M, Morén C, García-Otero L, López M, Guitart-Mampel M, Milisenda J, Coll O, Cardellach F, Gratacós E, Miró Ò and Garrabou G
Publicada:
1 ago 2017
Resumen:
To determine whether mitochondrial, oxidative, and apoptotic abnormalities in placenta derived from HIV and combined antiretroviral therapy (cART) containing zidovudine (AZT) could be associated with adverse perinatal outcome.
Filiaciones:
Hernández S:
*Department of Maternal-Fetal Medicine, BCNatal-Hospital Clínic, University of Barcelona, Spain and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER)
†Muscle Research and Mitochondrial Function Laboratory, Cellex IDIBAPS, Faculty of Medicine and Health Sciences, University of Barcelona, Internal Medicine Service-Hospital Clínic of Barcelona and CIBERER, Barcelona, Spain
and ‡Unit of Assisted Reproduction, Clínica Eugin, Barcelona, Spain
Open Access
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