Epidemiological and clinical characteristics of children hospitalized due to influenza A and B in the south of Europe, 2010-2016
Por:
Jané M, Vidal MJ, Soldevila N, Romero A, Martínez A, Torner N, Godoy P, Launes-Montana C, Rius C, Marcos MA and Dominguez A
Publicada:
6 sep 2019
Ahead of Print:
6 sep 2019
Categoría:
Multidisciplinary
Resumen:
Influenza produces annual epidemics that affect 5-15% of the world
population. Complications and hospitalizations are more frequent in
childhood. This study describes and analyses the epidemiological and
clinical characteristics of children hospitalized due to confirmed
influenza in influenza surveillance sentinel hospitals in Catalonia.
Retrospective descriptive study conducted in six influenza seasons
(2010-2011 to 2015-2016) in persons aged 0-17 years diagnosed with
laboratory-confirmed influenza requiring hospitalization. 291 cases were
notified to the health authorities: 79.4% were due to the influenza A
virus and 20.6% to the B virus. The most common subtype was H1N1 with
57.6% of cases: 52.6% were male, 56.7% were aged < 2 years, and 24.4%
were aged < 1 year. 62.2% of cases had pneumonia, 26.8% acute
respiratory distress syndrome and 11.7% bacterial pneumonia. 5.8% of
cases were vaccinated and 21.3% required intensive care unit admission,
of whom 54.8% were aged < 2 years. There were 3 deaths, all with
influenza A infection. Influenza A cases were younger than influenza B
cases (OR 3.22; 95% CI: 1.73-6.00). Conclusion: Children aged < 2 years
are especially vulnerable to the A H1N1 virus, including those without
pre-existing chronic disease. These results are relevant for the
planning of vaccination programs to improve maternal and child health.
Filiaciones:
Jané M:
Public Health Agency of Catalonia. Department of Health, Barcelona, Spain.
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain.
Vidal MJ:
Public Health Agency of Catalonia. Department of Health, Barcelona, Spain
Soldevila N:
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Department of Medicine, University of Barcelona, Barcelona, Spain
Romero A:
Department of Medicine, University of Barcelona, Barcelona, Spain
Martínez A:
Public Health Agency of Catalonia. Department of Health, Barcelona, Spain
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Torner N:
Public Health Agency of Catalonia. Department of Health, Barcelona, Spain
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Godoy P:
Public Health Agency of Catalonia. Department of Health, Barcelona, Spain
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Launes-Montana C:
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Sant Joan de Deu Children's Hospital, Esplugues de Llobregat, Spain
Rius C:
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Public Health Agency of Barcelona, Barcelona, Spain
Marcos MA:
Hospital Clinic of Barcelona, Barcelona, Spain
Dominguez A:
CIBER Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Madrid, Spain
Department of Medicine, University of Barcelona, Barcelona, Spain
Green Published, gold
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