3D printed soft surgical planning prototype for a biliary tract rhabdomyosarcoma
Por:
Tejo-Otero A, Lustig-Gainza P, Fenollosa-Artés F, Valls-Esteve A, Krauel L and Buj-Corral I
Publicada:
1 sep 2020
Ahead of Print:
11 may 2020
Resumen:
Biliary tract rhabdomyosarcoma is a soft tissue malignant
musculoskeletal tumor which is located in the biliary tract. Although
this tumor represents less than 1% of the total amount of childhood
cancers, when localized, a 70% overall 5-year survival rate, the
resection is clinically challenging and complications might exist during
the biliary obstruction. Although surgery remains a mainstay, complete
tumor resection is generally difficult to achieve without mutilation and
severe long-term sequelae. Therefore, manufacturing multi-material 3D
surgical planning prototypes of the case provides a great opportunity
for surgeons to learn beforehand what they can expect. Additionally,
practicing before the operation enhances the probability of success.
That is why different compositions of materials have been characterized
to match the mechanical properties of the liver. To do this, Dynamic
Mechanical Analysis (DMA) tests and Shore hardness tests have been
carried out. Amongst the material samples produced, 6%wt PVA (poly vinyl
alcohol)/1%wt PHY (Phytagel)-1FT (Freeze-Thaw cycles) and 1%wt agarose
appear as the best options for mimicking the liver tissue in terms of
viscoelasticity. Regarding the Shore hardness, the best solution is 1%wt
agarose. Additionally, a surgical planning prototype using this last
material mentioned was manufactured and validated using a CT (Computed
Tomography) scanner. In most of the structures the difference between
the 3D model and the organ in terms of dimensions is less than 3.35 mm,
which represents a low dimensional error, around 1%. On the other hand,
the total manufacturing cost of the 3D physical model was euro513 which
is relatively low in comparison with other technologies.
Filiaciones:
Tejo-Otero A:
Centre CIM, Universitat Politècnica de Catalunya (CIM UPC), Carrer de Llorens i Artigas, 12, 08028, Barcelona, Spain
Lustig-Gainza P:
Centre CIM, Universitat Politècnica de Catalunya (CIM UPC), Carrer de Llorens i Artigas, 12, 08028, Barcelona, Spain
Fenollosa-Artés F:
Centre CIM, Universitat Politècnica de Catalunya (CIM UPC), Carrer de Llorens i Artigas, 12, 08028, Barcelona, Spain
Universitat Politècnica de Catalunya, Departament of Mechanical Engineering. School of Engineering of Barcelona (ETSEIB), Av. Diagonal, 647, 08028, Barcelona, Spain
Krauel L:
Hospital Sant Joan de Déu, Barcelona, Spain
Buj-Corral I:
Universitat Politècnica de Catalunya, Departament of Mechanical Engineering. School of Engineering of Barcelona (ETSEIB), Av. Diagonal, 647, 08028, Barcelona, Spain
Green Submitted
|