Is loneliness associated with mild cognitive impairment in low- and middle-income countries?
Por:
Smith L, Bloska J, Jacob L., Barnett Y, Butler L, Trott M, Odell-Miller H, Veronese N, Kostev K, Bettac EL, Godier-McBard L and Koyanagi A
Publicada:
1 sep 2021
Ahead of Print:
23 mar 2021
Categoría:
Geriatrics and gerontology
Resumen:
BACKGROUND: Loneliness may be a risk factor for mild cognitive impairment but studies on this topic are scarce, particularly from low- and middle-income countries (LMICs). Therefore, the aim of the present study was to investigate the association between loneliness and mild cognitive impairment (MCI) in six LMICs (China, Ghana, India, Mexico, Russia and South Africa). METHODS: Cross-sectional, community-based, nationally representative data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. The definition of MCI was based on the National Institute on Ageing-Alzheimer's Association criteria. Multivariable logistic regression analysis and meta-analysis were conducted to assess associations. RESULTS: The final analytical sample consisted of 19,092 and 13,623 individuals aged 50-64 years (middle-aged adults) and =65 years (older adults), respectively. Among the middle-aged, overall, loneliness was associated with a non-significant 1.43 (95% confidence interval [CI] = 0.93-2.21) times higher odds for MCI although significant associations were observed in China (OR = 1.51; 95%CI = 1.08-2.09) and South Africa (OR = 3.87; 95%CI = 1.72-8.71). As for older adults, overall, there was a significant association between loneliness and MCI (OR = 1.52; 95%CI = 1.12-2.07). CONCLUSION: In this large representative sample of middle-aged and older adults from multiple LMICs, findings suggest that loneliness is associated with MCI. It may be prudent to consider reducing loneliness in low-economic settings to aid in the prevention of MCI and ultimately dementia.
Filiaciones:
Smith L:
The Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, UK
Bloska J:
Cambridge Institute for Music Therapy Research, Anglia Ruskin University, Cambridge, UK
Jacob L.:
Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona, 08830, Spain
Faculty of Medicine, University of Versailles Saint-Quentin-en-Yvelines, Montigny-le-Bretonneux, 78180, France
Barnett Y:
Anglia Ruskin University, Cambridge, UK
Butler L:
Faculty of Science and Engineering, Anglia Ruskin University, Cambridge, UK
Trott M:
The Cambridge Centre for Sport and Exercise Sciences, Anglia Ruskin University, Cambridge, UK
Odell-Miller H:
Cambridge Institute for Music Therapy Research, Anglia Ruskin University, Cambridge, UK
Veronese N:
Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy
Kostev K:
Philipps University of Marburg, Marburg, Germany
Bettac EL:
Department of Psychology, Washnington State University Vancouver, 14204, NE, Salmon Creek Avenue, , Vancouver,, WA, USA
Godier-McBard L:
Veterans and Families Institute for Military Social Research, Anglia Ruskin University, Chelmsford, UK
Koyanagi A:
Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona, 08830, Spain
ICREA, Pg. Lluís Companys 23, Barcelona, Spain
Green Accepted
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