Consensus-driven conceptual development of a standardized whole body-MRI scoring system for assessment of disease activity in juvenile idiopathic arthritis: MRI in JIA OMERACT working group
Por:
Panwar J, Tolend M, Redd B, Srinivasalu H, Colbert RA, Akikusa J, Appenzeller S, Carrino JA, Herregods N, Jans L, Highmore K, von Kalle T, Kirkhus E, Rumsey DG, Jaremko JL, Inarejos E, van Rossum MA, Stimec J, Tse SM, Twilt M, Tzaribachev N, Sudol-Szopinska I, Meyers AB and Doria AS
Publicada:
1 dic 2021
Ahead of Print:
15 ago 2021
Categoría:
Anesthesiology and pain medicine
Resumen:
Objectives: Whole body-MRI is helpful in directing diagnostic and treatment approaches, and as a research outcome measure. We describe our initial consensus-driven phase towards developing a whole body-MRI scoring system for juvenile idiopathic arthritis.
Methods: An iterative approach using three rounds of anonymous Delphi surveys followed by a consensus meeting was used to draft the structure of the whole body-MRI scoring system, including the relevant anatomic joints and entheses for assessment, diagnostic item selection, definition and grading, and selection of appropriate MRI planes and sequences. The surveys were completed independently by an international expert group consisting of pediatric radiologists and rheumatologists.
Results: Twenty-two experts participated in at least one of three rounds of Delphi surveys and a concluding consensus meeting. A first iteration scoring system was developed which ultimately included the assessment of 100 peripheral, 23 chest, and 76 axial joints, and 64 entheses, with 2-4 diagnostic items graded in each of the items, using binary (presence/absence) and 2-3-level ordinal scores. Recommendations on anatomic MRI planes and sequences were specified as the minimally necessary imaging protocol for the scoring system.
Conclusion: A novel whole body-MRI scoring system for juvenile idiopathic arthritis was developed by consensus among members of MRI in JIA OMERACT working group. Further iterative refinements, reliability testing, and responsiveness are warranted in upcoming studies. (c) 2021 Elsevier Inc. All rights reserved.
Filiaciones:
Panwar J:
Department of Radiology, Christian Medical College, Vellore, India
Tolend M:
Department of Diagnostic Imaging, Research Institute, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada
Redd B:
Department of Radiology, Clinical Center, NIH, Bethesda, Maryland, United States
Srinivasalu H:
Division of Rheumatology, Children's National Hospital and George Washington University School of Medicine, Washington, DC, United States
Colbert RA:
Pediatric Translational Research Branch, Musculoskeletal and Skin Diseases, National Institute of Arthritis, NIH, Bethesda, MD, United States
Akikusa J:
Rheumatology Service, Department of General Medicine, Royal Children's Hospital Melbourne, Australia
Appenzeller S:
Faculty of Medical Sciences, University of Campinas, Campinas, Brazil
Carrino JA:
Department of Radiology, Hospital for Special Surgery, New York, United States
Herregods N:
Department of Radiology, Ghent University, Ghent, Belgium
Jans L:
Department of Radiology, Ghent University, Ghent, Belgium
Highmore K:
Department of Radiology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada
von Kalle T:
RadiologischesInstitut, Olga Hospital Klinikum, Stuttgart, Germany
Kirkhus E:
Department of Radiology, Oslo University Hospital, Oslo, Norway
Rumsey DG:
Division of Rheumatology, Stollery Children's Hospital, University of Alberta, Canada
Jaremko JL:
Department of Radiology & Diagnostic Imaging, Stollery Children's Hospital, University of Alberta, Canada
Inarejos E:
Department of Radiology, Hospital Sant Joan de Déu, Barcelona, Spain
van Rossum MA:
Amsterdam Rheumatology and Immunology Center, Reade, and Emma Children's Hospital Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
Stimec J:
Department of Diagnostic Imaging, Research Institute, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada
Tse SM:
Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Twilt M:
Department of Pediatrics, Division of Rheumatology, Alberta Children's Hospital, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
Tzaribachev N:
Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany
Sudol-Szopinska I:
National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw,Poland
Meyers AB:
Department of Radiology, Cincinnati Children's Hospital, Cincinnati, OH, United States
Doria AS:
Department of Diagnostic Imaging, Research Institute, The Hospital for Sick Children, Department of Medical Imaging, University of Toronto, Toronto, ON, Canada
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