Heterogeneity in Response to MCT and Psychoeducation: A Feasibility Study Using Latent Class Mixed Models in First-Episode Psychosis.
Por:
Ferrer-Quintero M, Fernández D, López-Carrilero R, Diaz L, Verdaguer M, García-Mieres H, Huerta-Ramos ME, Gómez-Benito J, Peláez MT, Birulés-Muntané I, Barajas A, Esther Pousa Tomas, Barrigón M, Gutiérrez-Zotes A, Eva Maria Grasa Bello, Isabel Ruiz Delgado, ESTHER LORENTE ROVIRA, Jordi Cid Colom, On Behalf Of The Spanish Metacognition Study Group and Ochoa S
Publicada:
28 oct 2022
Ahead of Print:
28 oct 2022
Resumen:
Metacognitive training (MCT) is an effective treatment for psychosis. Longitudinal trajectories of treatment response are unknown but could point to strategies to maximize treatment efficacy during the first episodes. This work aims to explore the possible benefit of using latent class mixed models (LCMMs) to understand how treatment response differs between metacognitive training and psychoeducation. We conducted LCMMs in 28 patients that received MCT and 34 patients that received psychoeducation. We found that MCT is effective in improving cognitive insight in all patients but that these effects wane at follow-up. In contrast, psychoeducation does not improve cognitive insight, and may increase self-certainty in a group of patients. These results suggest that LCMMs are valuable tools that can aid in treatment prescription and in predicting response to specific treatments.
Filiaciones:
:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Department of Social and Quantitative Psychology, Faculty of Psychology, University of Barcelona, 08035 Barcelona, Spain
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
:
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Serra Húnter Fellow, Department of Statistics and Operations Research (DEIO), Universitat Politècnica de Catalunya, 08028 Barcelona, Spain
Institute of Mathematics of UPC-BarcelonaTech (IMTech), 08028 Barcelona, Spain
López-Carrilero R:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Sant Joan de Déu Research Foundation, 08950 Esplugues de Llobregat, Spain
Diaz L:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Sant Joan de Déu Research Foundation, 08950 Esplugues de Llobregat, Spain
COMSAL Research Group, Psychology Department, FPCEE Blanquerna, Ramon Llull University, 08022 Barcelona, Spain
Verdaguer M:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Sant Joan de Déu Research Foundation, 08950 Esplugues de Llobregat, Spain
Departament de Psicologia Clínica i de la Salut, Facultat de Psicologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
García-Mieres H:
Health Services Research Group, Instituto Hospital del Mar de Investigaciones Médicas, 08003 Barcelona, Spain
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública, Instituto de Salud Carlos III, 28029 Madrid, Spain
Departamento de Medicina y Ciencias de la Vida, Universitat Pompeu Fabra, 08003 Barcelona, Spain
Huerta-Ramos ME:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Gómez-Benito J:
Department of Social and Quantitative Psychology, Faculty of Psychology, University of Barcelona, 08035 Barcelona, Spain
Grupo de Estudios de Invariancia de la Medida y Análisis del Cambio (GEIMAC), Institut de Neurociències, Universitat de Barcelona, 08035 Barcelona, Spain
Peláez MT:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Birulés-Muntané I:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Department of Social and Quantitative Psychology, Faculty of Psychology, University of Barcelona, 08035 Barcelona, Spain
Barajas A:
Serra Húnter Fellow Departament de Psicologia Clínica i de la Salut, Facultat de Psicologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
Department of Research, Centre d'Higiene Mental Les Corts, 08029 Barcelona, Spain
Esther Pousa Tomas:
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica-Sant Pau (IIB-Sant Pau), 08025, Barcelona, Spain
Barrigón M:
Departament of Psychiatry, University Hospital Virgen del Rocio, 41013 Seville, Spain
Gutiérrez-Zotes A:
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Hospital Universitari Institut Pere Mata, Institut d'Investigació Sanitària Pere Virgili, CERCA, Universitat Rovira i Virgili, Reus, Spain, 43206 Reus, Spain
Eva Maria Grasa Bello:
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica-Sant Pau (IIB-Sant Pau), 08025, Barcelona, Spain
Isabel Ruiz Delgado:
Unidad de Salud Mental Comunitaria Malaga Norte, 29014 Málaga, Spain
ESTHER LORENTE ROVIRA:
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Psychiatry Service, Hospital Clínico Universitario de Valencia, 46010 Valencia, Spain
Jordi Cid Colom:
Mental Health & Addiction Research Group, IdiBGi, Institut d'Assistencia Sanitària, 17190 Girona, Spain
Ochoa S:
Parc Sanitari Sant Joan de Déu, Sant Boi de Llobregat, 08830 Barcelona, Spain
Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, 28029 Madrid, Spain
Green Published, gold
|