Chronic physical conditions, physical multimorbidity, and quality of life among adults aged = 50 years from six low- and middle-income countries.
Por:
Olanrewaju O, Trott M, Smith L, López Sánchez GF, Carmichael C, Hans Oh, Schuch F, Jacob L., Veronese N, Soysal P, Shin JI, Butler L, Barnett Y and Koyanagi A
Publicada:
1 abr 2023
Ahead of Print:
26 dic 2022
Categoría:
Public health, environmental and occupational health
Resumen:
PURPOSE: Multimorbidity (i.e., = 2 chronic conditions) poses a challenge for health systems and governments, globally. Several studies have found inverse associations between multimorbidity and quality of life (QoL). However, there is a paucity of studies from low- and middle-income countries (LMICs), especially among the older population, as well as studies examining mediating factors in this association. Thus, the present study aimed to explore the associations, and mediating factors, between multimorbidity and QoL among older adults in LMICs. METHODS: Cross-sectional nationally representative data from the Study on Global Ageing and Adult Health were analyzed. A total of 11 chronic conditions were assessed. QoL was assessed with the 8-item WHO QoL instrument (range 0-100) with higher scores representing better QoL. Multivariable linear regression and mediation analyses were conducted to assess associations. RESULTS: The final sample consisted of 34,129 adults aged = 50 years [mean (SD) age 62.4 (16.0) years; age range 50-114 years; 52.0% females]. Compared to no chronic conditions, 2 (b-coefficient - 5.89; 95% CI - 6.83, - 4.95), 3 (- 8.35; - 9.63, - 7.06), 4 (- 10.87; - 12.37, - 9.36), and = 5 (- 13.48; - 15.91, - 11.06) chronic conditions were significantly associated with lower QoL, dose-dependently. The mediation analysis showed that mobility (47.9%) explained the largest proportion of the association between multimorbidity and QoL, followed by pain/discomfort (43.5%), sleep/energy (35.0%), negative affect (31.9%), cognition (20.2%), self-care (17.0%), and interpersonal activities (12.0%). CONCLUSION: A greater number of chronic conditions was associated with lower QoL dose-dependently among older adults in LMICs. Public health and medical practitioners should aim to address the identified mediators to improve QoL in patients with multimorbidity.
Filiaciones:
Olanrewaju O:
Cambridge Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, CB1 1PT, UK
Trott M:
Centre for Public Health, Queens University Belfast, Belfast, UK
Smith L:
Cambridge Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, CB1 1PT, UK.
López Sánchez GF:
Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain.
Carmichael C:
Cambridge Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, CB1 1PT, UK
Hans Oh:
Suzanne Dworak Peck School of Social Work, University of Southern California, Los Angeles, CA, 90007, USA
Schuch F:
Department of Sports Methods and Techniques, Federal University of Santa Maria, Santa Maria, Brazil
Faculty of Health Sciences, Universidad Autónoma de Chile, Providencia, Chile
Jacob L.:
Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, 08830, Barcelona, Spain
Veronese N:
Department of Internal Medicine and Geriatrics, University of Palermo, 90133, Palermo, Italy
Soysal P:
Department of Geriatric Medicine, Bezmialem Vakif University, 34093, Istanbul, Turkey
Shin JI:
Department of Pediatrics, Yonsei University College of Medicine, Yonsei-Ro 50, Seodaemun-Gu, C.P.O Box 8044, Seoul, 03722, Republic of Korea
Butler L:
Cambridge Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, CB1 1PT, UK
Barnett Y:
Cambridge Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, CB1 1PT, UK
Koyanagi A:
Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, 08830, Barcelona, Spain
ICREA, Pg, Lluis Companys 23, 08010, Barcelona, Spain
hybrid, Green Published
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