The association of physical multimorbidity with suicidal ideation and suicide attempts in England: A mediation analysis of influential factors.
Por:
Smith L, Shin JI, Lee S, Oh JW, López Sánchez GF, Kostev K, Jacob L., Tully MA, Schuch F, McDermott DT, Pizzol D, Veronese N, Song J, Soysal P and Koyanagi A
Publicada:
1 may 2023
Ahead of Print:
13 dic 2022
Resumen:
BACKGROUND: Suicide is one of the most important causes of deaths in the United Kingdom, and the numbers are currently increasing. AIM: There are numerous identified determinants of suicidality, and physical multimorbidity is potentially important but is currently understudied. Thus, this study aims to investigate the association of physical multimorbidity with suicidality. METHODS: Cross-sectional data from the Adult Psychiatric Morbidity Survey 2007, which was conducted in England between October 2006 and December 2007 by the National Center for Social Research and Leicester University were analyzed. Respondents were asked about 20 physical health conditions, and suicidal ideation and suicide attempts were assessed. RESULTS: Out of 7,403 individuals aged 16 years or over, the prevalence of physical multimorbidity, suicidal ideation, and suicide attempts were 35.1%, 4.3%, and 0.7%, respectively. After adjustment for potential confounders, compared to no physical conditions, 1, 2, 3, and ?4 conditions were associated with significant 1.79 (95% CI [1.25, 2.57]), 2.39 (95% CI [1.63, 3.51]), 2.88 (95% CI [1.83, 4.55]), and 6.29 (95% CI [4.12, 9.61]) times higher odds for suicidal ideation. Mediation analysis showed that cognitive problems (mediated percentage 39.2%) and disability (37.5%) explained the largest proportion between multimorbidity and suicidal ideation. Pain (38.0%) and cognitive problems (30.7%) explained the largest proportion between multimorbidity and suicide attempts. CONCLUSION: In this large sample of UK adults, physical multimorbidity was associated with significantly higher odds for suicidal ideation and suicide attempts. Moreover, several potential mediators were identified, and these may serve as future targets for interventions that aim to prevent suicidality among people with physical multimorbidity.
Filiaciones:
Smith L:
Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, UK
Shin JI:
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea
Lee S:
Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Republic of Korea
Oh JW:
Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Republic of Korea
López Sánchez GF:
Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Spain
Kostev K:
Philipps University of Marburg, Germany
Jacob L.:
Research and Development Unit, Parc Sanitari Sant Joan de Deu, CIBERSAM, ISCIII, Barcelona, Spain
Faculty of Medicine, University of Versailles Saint-Quentin-en-Yvelines, France
Tully MA:
School of Medicine, Ulster University, Londonderry, Northern Ireland, UK
Schuch F:
Department of Sports Methods and Techniques, Federal University of Santa Maria, Brazil
McDermott DT:
NTU Psychology, School of Social Sciences, Nottingham Trent University, UK
Pizzol D:
Italian Agency for Development Cooperation, Khartoum, Sudan
Veronese N:
Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science King Saud University, Riyadh, Saudi Arabia
Department of Internal Medicine, University of Palermo, Geriatrics Section, Italy
Song J:
Keimyung University School of Medicine, Daegu, Republic of Korea
Soysal P:
Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey
Koyanagi A:
Research and Development Unit, Parc Sanitari Sant Joan de Deu, CIBERSAM, ISCIII, Barcelona, Spain
ICREA, Barcelona, Spain
Green Submitted, Green Accepted
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