Dynapenic abdominal obesity and susceptibility to fall: a prospective analysis of the Osteoarthritis Initiative
Por:
Veronese N, Koyanagi A, Soysal P, Bolzetta F, Dominguez LJ, Barbagallo M, Sabico S, Al-Daghri NM and Smith L
Publicada:
5 may 2023
Ahead of Print:
5 may 2023
Resumen:
BackgroundThe prediction of the risk of falling remains a challenge in geriatric medicine and the identification of new potential reversible risk factors is a public health priority. In this study, we aim to investigate the association between DAO (dynapenic abdominal obesity) and incident falls in a large sample of people with knee OA (osteoarthritis) or at high risk for this condition, over 8 years of follow-up. MethodsDAO was defined using a waist circumference more than 102 cm in men and 88 cm in women and a concomitant presence of dynapenia, defined as a time over 15 s in the five times chair stands time. Falls, during follow-up, were recorded using self-reported information in the previous year. A logistic binary regression analysis was run, adjusted for potential confounders at the baseline, reporting the data as odds ratios (ORs) with their 95% confidence intervals (CIs). ResultsOverall, 3,844 subjects were included, majority of whom had abdominal obesity. Across the 8 years of follow-up, 2,695 participants fell vs. 1,149 not reporting any fall. Taking those without DAO as reference, the presence of only dynapenia was not associated with risk of falls (OR = 1.18;95%CI: 0.73-1.91; p = 0.50), whilst the presence of abdominal obesity (OR = 1.30; 95%CI: 1.09-1.56; p = 0.004) and DAO (OR = 1.31; 95%CI:1.01-1.73; p = 0.04) were significantly associated with a higher risk of incident falls. ConclusionDAO significantly increased risk of falls as well as the presence of abdominal obesity.
Filiaciones:
Veronese N:
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy
Koyanagi A:
Research and Development Unit, Parc Sanitari Sant Joan de Deu, CIBERSAM, ISCIII, Barcelona, Spain
ICREA, Barcelona, Spain
Soysal P:
Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey
Bolzetta F:
Medical Department, Geriatric Unit, Azienda ULSS (Unità Locale Socio Sanitaria) 3 "Serenissima", Venice, Italy
Dominguez LJ:
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy
Faculty of Medicine and Surgery, Kore University of Enna, Enna, Italy
Barbagallo M:
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy
Sabico S:
Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia
Al-Daghri NM:
Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, Saudi Arabia
Smith L:
Centre for Health, Performance, and Wellbeing, Anglia Ruskin University, Cambridge, United Kingdom
Green Accepted, gold, Green Published
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