Palladium Nanoparticles Synthesized by Laser Ablation in Liquids for Antimicrobial Applications
Por:
Fernandez-Arias, M, Vilas, AM, Boutinguiza, M, Rodríguez-Rius D, Arias-Gonzalez, F, Pou-Alvarez, P, Riveiro, A, Gil, J and Pou, J
Publicada:
1 ago 2022
Resumen:
Antibiotic resistance is a leading cause of death worldwide. In this paper, we explore new alternatives in the treatment of infections. Noble metal nanoparticles could help to mitigate this problem. In this work, palladium nanoparticles were synthesized by laser ablation in order to explore their antimicrobial capacity. To obtain palladium nanoparticles, a palladium plate immersed in water, or methanol, was ablated, using two pulsed lasers that emit radiation with wavelengths of 532 nm and 1064 nm, respectively. Pure Pd-NPs with crystalline microstructure and rounded shape were obtained. The nanoparticles' size is more homogeneous if the laser wavelength is 532 nm, and it decreases when methanol is used as solvent, reaching mean diameters smaller than 6 nm. With the objective of studying antimicrobial activity against Staphylococcus aureus, the Pd-NPs were immobilized on the surface of titanium discs. The release of palladium ions was recorded during the first seven days, and the cytotoxicity of the immobilized NPs was also tested with L929 mouse fibroblast cell line. Palladium nanoparticles synthesized by means of the infrared laser in methanol showed a strong inhibitory effect on S. aureus and good cytocompatibility, with no toxic effect on fibroblast cells.
Filiaciones:
Fernandez-Arias, M:
Univ Vigo, Sch Engn, LaserON Res Grp, CINTECX, E-36310 Vigo, Spain
Vilas, AM:
Univ Vigo, Sch Engn, LaserON Res Grp, CINTECX, E-36310 Vigo, Spain
Boutinguiza, M:
Univ Vigo, Sch Engn, LaserON Res Grp, CINTECX, E-36310 Vigo, Spain
SERGAS UVIGO, Galicia Hlth Res Inst IIS Galicia, E-36310 Vigo, Spain
Rodríguez-Rius D:
UPC Barcelona TECH, Mat Sci & Met Engn Dept, Biomat Biomech & Tissue Engn Grp, Barcelona 08930, Spain
Arias-Gonzalez, F:
Univ Int Catalunya, Sch Dent, Barcelona 08017, Spain
Pou-Alvarez, P:
Univ Vigo, Sch Engn, LaserON Res Grp, CINTECX, E-36310 Vigo, Spain
Riveiro, A:
Univ Vigo, Sch Engn, LaserON Res Grp, CINTECX, E-36310 Vigo, Spain
Pou, J:
Univ Vigo, Sch Engn, LaserON Res Grp, CINTECX, E-36310 Vigo, Spain
SERGAS UVIGO, Galicia Hlth Res Inst IIS Galicia, E-36310 Vigo, Spain
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