Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017


Por: Soriano, Joan B., Kendrick, Parkes J., Paulson, Katherine R., Gupta, Vinay, Vos, Theo, Abrams, Elissa M., Adedoyin, Rufus Adesoji, Adhikari, Tara Ballav, Advani, Shailesh M., Agrawal, Anurag, Ahmadian, Elham, Alahdab, Fares, Aljunid, Syed Mohamed, Altirkawi, Khalid A., Alvis-Guzman, Nelson, Anber, Nahla Hamed, Andrei, Catalina Liliana, Anjomshoa, Mina, Ansari, Fereshteh, Anto, Josep M., Arabloo, Jalal, Athari, Seyyede Masoume, Athari, Seyyed Shamsadin, Awoke, Nefsu, Badawi, Alaa, Banoub, Joseph Adel Mattar, Bennett, Derrick A., Bensenor, Isabela M., Berfield, Kathleen Sachiko, Bernstein, Robert S., Bhattacharyya, Krittika, Bijani, Ali, Brauer, Michael, Bukhman, Gene, Butt, Zahid A., Camera, Luis Alberto, Car, Josip, Carrero, Juan J., Carvalho, Felix, Castaneda-Orjuela, Carlos A., Choi, Jee-Young Jasmine, Christopher, Devasahayam J., Cohen, Aaron J., Dandona, Lalit, Dandona, Rakhi, Dang, Anh Kim, Daryani, Ahmad, de Courten, Barbora, Demeke, Feleke Mekonnen, Demoz, Gebre Teklemariam, De Neve, Jan-Walter, Desai, Rupak, Dharmaratne, Samath Dhamminda, Diaz, Daniel, Douiri, Abdel, Driscoll, Tim Robert, Duken, Eyasu Ejeta, Eftekhari, Aziz, Elkout, Hajer, Endries, Aman Yesuf, Fadhil, Ibtihal, Faro, Andre, Farzadfar, Farshad, Fernandes, Eduarda, Filip, Irina, Fischer, Florian, Foroutan, Masoud, Garcia-Gordillo, M. A., Gebre, Abadi Kahsu, Gebremedhin, Ketema Bizuwork, Gebremeskel, Gebreamlak Gebremedhn, Gezae, Kebede Embaye, Ghoshal, Aloke Gopal, Gill, Paramjit Singh, Gillum, Richard F., Goudarzi, Houman, Guo, Yuming, Gupta, Rajeev, Hailu, Gessessew Bugssa, Hasanzadeh, Amir, Hassen, Hamid Yimam, Hay, Simon I., Hoang, Chi Linh, Hole, Michael K., Horita, Nobuyuki, Hosgood, H. Dean, Hostiuc, Mihaela, Househ, Mowafa, Ilesanmi, Olayinka Stephen, Ilic, Milena D., Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Jakovljevic, Mihajlo, Jamal, Amr A., Jha, Ravi Prakash, Jonas, Jost B., Kabir, Zubair, Kasaeian, Amir, Kasahun, Gebremicheal Gebreslassie, Kassa, Getachew Mullu, Kefale, Adane Teshome, Kengne, Andre Pascal, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khan, Ejaz Ahmad, Khan, Junaid, Khubchandani, Jagdish, Kim, Young-Eun, Kim, Yun Jin, Kisa, Sezer, Kisa, Adnan, Knibbs, Luke D., Komaki, Hamidreza, Koul, Parvaiz A., Koyanagi A, Kumar, G. Anil, Lan, Qing, Lasrado, Savita, Lauriola, Paolo, La Vecchia, Carlo, Tham Thi Le, Leigh, James, Levi, Miriam, Li, Shanshan, Lopez, Alan D., Lotufo, Paulo A., Madotto, Fabiana, Mahotra, Narayan B., Majdan, Marek, Majeed, Azeem, Malekzadeh, Reza, Mamun, Abdullah A., Manafi, Navid, Manafi, Farzad, Mantovani, Lorenzo Giovanni, Meharie, Birhanu Geta, Meles, Hagazi Gebre, Meles, Gebrekiros Gebremichael, Menezes, Ritesh G., Mestrovic, Tomislav, Miller, Ted R., Mini, G. K., Mirrakhimov, Erkin M., Moazen, Babak, Mohammad, Karzan Abdulmuhsin, Mohammed, Shafiu, Mohebi, Farnam, Mokdad, Ali H., Molokhia, Mariam, Monasta, Lorenzo, Moradi, Masoud, Moradi, Ghobad, Morawska, Lidia, Mousavi, Seyyed Meysam, Musa, Kamarul Imran, Mustafa, Ghulam, Naderi, Mehdi, Naghavi, Mohsen, Naik, Gurudatta, Nair, Sanjeev, Nangia, Vinay, Nansseu, Jobert Richie, Nazari, Javad, Ndwandwe, Duduzile Edith, Negoi, Ruxandra Irina, Trang Huyen Nguyen, Cuong Tat Nguyen, Huong Lan Thi Nguyen, Nixon, Molly R., Ofori-Asenso, Richard, Ogbo, Felix Akpojene, Olagunju, Andrew T., Olagunju, Tinuke O., Oren, Eyal, Ortiz, Justin R., Owolabi, Mayowa O., Mahesh, P. A., Pakhale, Smita, Pana, Adrian, Panda-Jonas, Songhomitra, Park, Eun-Kee, Hai Quang Pham, Postma, Maarten J., Pourjafar, Hadi, Poustchi, Hossein, Radfar, Amir, Rafiei, Alireza, Rahim, Fakher, Rahman, Mohammad Hifz Ur, Rahman, Muhammad Aziz, Rawaf, Salman, Rawaf, David Laith, Rawal, Lal, Reiner, Jr., Robert C., Reitsma, Marissa Bettay, Roever, Leonardo, Ronfani, Luca, Roro, Elias Merdassa, Roshandel, Gholamreza, Rudd, Kristina E., Sabde, Yogesh Damodar, Sabour, Siamak, Saddik, Basema, Safari, Saeed, Saleem, Komal, Samy, Abdallah M., Santric-Milicevic, Milena M., Jose, Bruno Piassi Sao, Sartorius, Benn, Satpathy, Maheswar, Savic, Miloje, Sawhney, Monika, Sepanlou, Sadaf G., Shaikh, Masood Ali, Sheikh, Aziz, Shigematsu, Mika, Shirkoohi, Reza, Si, Si, Siabani, Soraya, Singh, Virendra, Singh, Jasvinder A., Soljak, Michael, Somayaji, Ranjani, Soofi, Moslem, Soyiri, Ireneous N., Tefera, Yonatal Mesfin, Temsah, Mohamad-Hani, Tesfay, Berhe Etsay, Thakur, Jarnail Singh, Toma, Alemayehu Toma, Tortajada-Girbes, Miguel, Khanh Bao Tran, Bach Xuan Tran, Car, Lorainne Tudor, Ullah, Irfan, Vacante, Marco, Valdez, Pascual R., van Boven, Job F. M., Vasankari, Tommi Juhani, Veisani, Yousef, Violante, Francesco S., Wagner, Gregory R., Westerman, Ronny, Wolfe, Charles D. A., Wondafrash, Dawit Zewdu, Wondmieneh, Adam Belay, Yonemoto, Naohiro, Yoon, Seok-Jun, Zaidi, Zoubida, Zamani, Mohammad, Zar, Heather J. and Zhang, Yunquan

Publicada: 1 jun 2020
Categoría: Pulmonary and respiratory medicine

Resumen:
Background Previous attempts to characterise the burden of chronic respiratory diseases have focused only on specific disease conditions, such as chronic obstructive pulmonary disease (COPD) or asthma. In this study, we aimed to characterise the burden of chronic respiratory diseases globally, providing a comprehensive and up-to-date analysis on geographical and time trends from 1990 to 2017. Methods Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017, we estimated the prevalence, morbidity, and mortality attributable to chronic respiratory diseases through an analysis of deaths, disability-adjusted life-years (DALYs), and years of life lost (YLL) by GBD super-region, from 1990 to 2017, stratified by age and sex. Specific diseases analysed included asthma, COPD, interstitial lung disease and pulmonary sarcoidosis, pneumoconiosis, and other chronic respiratory diseases. We also assessed the contribution of risk factors (smoking, second-hand smoke, ambient particulate matter and ozone pollution, household air pollution from solid fuels, and occupational risks) to chronic respiratory disease-attributable DALYs. Findings In 2017, 544.9 million people (95% uncertainty interval [UI] 506.9- 584.8) worldwide had a chronic respiratory disease, representing an increase of 39.8% compared with 1990. Chronic respiratory disease prevalence showed wide variability across GBD super-regions, with the highest prevalence among both males and females in high-income regions, and the lowest prevalence in sub-Saharan Africa and south Asia. The age-sex- specific prevalence of each chronic respiratory disease in 2017 was also highly variable geographically. Chronic respiratory diseases were the third leading cause of death in 2017 (7.0% [95% UI 6.8-7 .2] of all deaths), behind cardiovascular diseases and neoplasms. Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578-4 044 819) in 2017, an increase of 18.0% since 1990, while total DALYs increased by 13.3%. However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14.3% decrease), agestandardised death rates (42.6%), and age-standardised DALY rates (38.2%). In males and females, most chronic respiratory disease-attributable deaths and DALYs were due to COPD. In regional analyses, mortality rates from chronic respiratory diseases were greatest in south Asia and lowest in sub-Saharan Africa, also across both sexes. Notably, although absolute prevalence was lower in south Asia than in most other super-regions, YLLs due to chronic respiratory diseases across the subcontinent were the highest in the world. Death rates due to interstitial lung disease and pulmonary sarcoidosis were greater than those due to pneumoconiosis in all super-regions. Smoking was the leading risk factor for chronic respiratory disease-related disability across all regions for men. Among women, household air pollution from solid fuels was the predominant risk factor for chronic respiratory diseases in south Asia and sub-Saharan Africa, while ambient particulate matter represented the leading risk factor in southeast Asia, east Asia, and Oceania, and in the Middle East and north Africa super-region. Interpretation Our study shows that chronic respiratory diseases remain a leading cause of death and disability worldwide, with growth in absolute numbers but sharp declines in several age-standardised estimators since 1990. Premature mortality from chronic respiratory diseases seems to be highest in regions with less-resourced health systems on a per-capita basis. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.

Filiaciones:
Soriano, Joan B.:
 Univ Autonoma Madrid, Hosp Univ Princesa, Madrid 28005, Spain

 CIBERES, Madrid, Spain

Kendrick, Parkes J.:
 Reiner, Robert C

Paulson, Katherine R.:
 Reiner, Robert C

Gupta, Vinay:
 Reiner, Robert C

Vos, Theo:
 Reiner, Robert C

Abrams, Elissa M.:
 Univ Manitoba, Sect Allergy & Clin Immunol, Winnipeg, MB, Canada

 Univ British Columbia, Dept Pediat, Vancouver, BC, Canada

Adedoyin, Rufus Adesoji:
 Obafemi Awolowo Univ, Dept Med Rehab, Ife, Nigeria

Adhikari, Tara Ballav:
 Aarhus Univ, Dept Publ Hlth, Aarhus, Denmark

 Univ Southern Denmark, Nepal Hlth Frontiers, Kathmandu, Nepal

Advani, Shailesh M.:
 NIH, Social Behav Res Branch, Bldg 10, Bethesda, MD 20892 USA

 Georgetown Univ, Dept Oncol, Washington, DC USA

Agrawal, Anurag:
 CSIR, Inst Genom & Integrat Biol, Delhi, India

 Baylor Coll Med, Internal Med, Houston, TX 77030 USA

Ahmadian, Elham:
 Tabriz Univ Med Sci, Res Ctr Chron Kidney Dis, Tabriz, Iran

 Joint Ukraine Azerbaijan Int Res & Educ Ctr Nanob, Baku, Azerbaijan

Alahdab, Fares:
 Mayo Clin, Fdn Med Educ & Res, Mayo Evidence Based Practice Ctr, Rochester, MN USA

Aljunid, Syed Mohamed:
 Kuwait Univ, Dept Hlth Policy & Management, Safat, Kuwait

 Natl Univ Malaysia, Int Ctr Casemix & Clin Coding, Bandar Tun Razak, Malaysia

Altirkawi, Khalid A.:
 King Saud Univ, Pediat Intens Care Unit, Riyadh, Saudi Arabia

Alvis-Guzman, Nelson:
 Univ Cartagena, Res Grp Hlth Econ, Cartagena, Colombia

 Univ Coast, Res Grp Hosp Management & Hlth Policies, Barranquilla, Colombia

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 Mansoura Univ, Fac Med, Mansoura, Egypt

 Mansoura Univ, Mansoura, Egypt

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 Carol Davila Univ Med & Pharm, Cardiol Dept, Bucharest, Romania

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 Rafsanjan Univ Med Sci, Social Determinants Hlth Res Ctr, Rafsanjan, Iran

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 AREEO, Razi Vaccine & Serum Res Inst, Tehran, Iran

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 Univ Pompeu Fabra, Dept Expt & Hlth Sci, Barcelona, Spain

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 Iran Univ Med Sci, Hlth Management & Econ Res Ctr, Tehran, Iran

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 Zanjan Univ Med Sci, Dept Immunol, Zanjan, Iran

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 Maragheh Univ Med Sci, Dept Biol, Maragheh, Iran

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 Wolaita Sodo Univ, Dept Nursing, Wolaita Sodo, Ethiopia

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 Univ Toronto, Dept Nutr Sci, Toronto, ON, Canada

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 Univ London, Dept Internal Med, London, England

 Alexandria Univ, Dept Gen Med, Alexandria, Egypt

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 Dept Vet Affairs, Thorac Surg, Seattle, WA USA

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 Emory Univ, Hubert Dept Global Hlth, Atlanta, GA 30322 USA

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 Natl Inst Biomed Genom, Dept Stat & Computat Genom, Kalyani, W Bengal, India

 Univ Calcutta, Dept Stat, Kolkata, India

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 Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada

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 Harvard Univ, Dept Global Hlth & Social Med, Boston, MA 02115 USA

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 Al Shifa Trust Eye Hosp, Al Shifa Sch Publ Hlth, Rawalpindi, Pakistan

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 Argentine Soc Med, Buenos Aires, DF, Argentina

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 Nanyang Technol Univ, Ctr Populat Hlth Sci, Singapore, Singapore

 Imperial Coll London, Dept Primary Care & Publ Hlth, London, England

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 Seoul Natl Univ Hosp, Biomed Informat, Seoul, South Korea

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 Christian Med Coll & Hosp CMC, Dept Pulm Med, Vellore, Tamil Nadu, India

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 Hlth Effects Inst, Boston, MA USA

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 Publ Hlth Fdn India, Gurugram, India

 Indian Council Med Res, New Delhi, India

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 Duy Tan Univ, Inst Global Hlth Innovat, Hanoi, Vietnam

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 Monash Univ, Sch Clin Sci, Melbourne, Vic, Australia

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 Heidelberg Univ, HIGH, Heidelberg, Germany

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 Atlanta Vet Affairs Med Ctr, Div Cardiol, Decatur, GA USA

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 Univ Peradeniya, Dept Community Med, Peradeniya, Sri Lanka

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 Univ Nacl Autonoma Mexico, Ctr Complex Sci, Mexico City, DF, Mexico

 Autonomous Univ Sinaloa, Fac Vet Med & Zootechn, Culiacan Rosales, Mexico

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 Kings Coll London, Sch Populat Hlth & Environm Sci, London, England

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 Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia

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 Wollega Univ, Coll Hlth Sci, Nekemte, Ethiopia

 Jimma Univ, Mycobacteriol Res Ctr, Jimma, Ethiopia

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 Maragheh Univ Med Sci, Dept Pharmacol & Toxicol, Maragheh, Iran

 John Paul II Catholic Univ Lublin, Dept Pharmacol & Toxicol, Lublin, Poland

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 Tripoli Univ, Dept Community Med, Tripoli, Libya

 WHO, Hlth Informat, Tripoli, Libya

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 St Pauls Hosp Millennium Med Coll, Publ Hlth Dept, Addis Ababa, Ethiopia

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 Minist Publ Hlth & Populat, Div Noncommunicable Dis, Dubai, U Arab Emirates

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 Univ Fed Sergipe, Dept Psychol, Sao Cristovao, Brazil

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 Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran

Fernandes, Eduarda:
 Univ Porto, Associated Lab Green Chem LAQV, Porto, Portugal

Filip, Irina:
 Kaiser Permanente, Dept Psychiat, Fontana, CA USA

 AT Still Univ, Sch Hlth Sci, Mesa, AZ 85206 USA

Fischer, Florian:
 Ravensburg Weingarten Univ Appl Sci, Inst Gerontol Hlth Serv & Nursing Res, Weingarten, Germany

Foroutan, Masoud:
 Abadan Fac Med Sci, Dept Med Parasitol, Abadan, Iran

Garcia-Gordillo, M. A.:
 Autonomous Univ Chile, Fac Business & Management, Talca, Chile

Gebre, Abadi Kahsu:
 Mekelle Univ, Sch Pharm, Mekelle, Ethiopia

 Edith Cowan Univ, Sch Med & Hlth Sci, Perth, WA, Australia

Gebremedhin, Ketema Bizuwork:
 Addis Ababa Univ, Dept Nursing & Midwifery, Addis Ababa, Ethiopia

Gebremeskel, Gebreamlak Gebremedhn:
 Aksum Univ, Dept Nursing, Aksum, Ethiopia

 Mekelle Univ, Dept Nursing, Mekelle, Ethiopia

Gezae, Kebede Embaye:
 Mekelle Univ, Dept Biostat, Mekelle, Ethiopia

Ghoshal, Aloke Gopal:
 Natl Allergy Asthma Bronchitis Inst, Resp Med, Kolkata, India

 Fortis Hosp, Dept Resp Med, Kolkata, India

Gill, Paramjit Singh:
 Univ Warwick, Med Sch, Coventry, W Midlands, England

Gillum, Richard F.:
 Howard Univ, Div Gen Internal Med, Washington, DC 20059 USA

 Howard Univ, Dept Community & Family Med, Washington, DC 20059 USA

Goudarzi, Houman:
 Hokkaido Univ, Dept Resp Med, Sapporo, Hokkaido, Japan

 Hokkaido Univ, Ctr Environm & Hlth Sci, Sapporo, Hokkaido, Japan

Guo, Yuming:
 Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia

 Binzhou Med Univ, Dept Epidemiol, Yantai, Peoples R China

Gupta, Rajeev:
 Eternal Heart Care Ctr & Res Inst, Dept Prevent Cardiol, Jaipur, Rajasthan, India

 Mahatma Gandhi Univ Med Sci, Dept Med, Jaipur, Rajasthan, India

Hailu, Gessessew Bugssa:
 Mekelle Univ, Dept Med Parasitol & Entomol, Mekelle, Ethiopia

Hasanzadeh, Amir:
 Maragheh Univ Med Sci, Dept Microbiol, Maragheh, Iran

 Univ Tehran Med Sci, Dept Microbiol, Tehran, Iran

Hassen, Hamid Yimam:
 Univ Antwerp Hosp, Dept Primary & Interdisciplinary Care, Antwerp, Belgium

 Mizan Tepi Univ, Dept Publ Hlth, Mizan Teferi, Ethiopia

Hay, Simon I.:
 Reiner, Robert C

Hoang, Chi Linh:
 Nguyen Tat Thanh Univ, Ctr Excellence Behav Med, Ho Chi Minh City, Vietnam

Hole, Michael K.:
 Univ Texas Austin, Dept Pediat, Austin, TX 78712 USA

Horita, Nobuyuki:
 Yokohama City Univ, Dept Pulmonol, Kanazawa Ku, Yokohama, Kanagawa, Japan

 NIH, NHGRI, Bldg 10, Bethesda, MD 20892 USA

Hosgood, H. Dean:
 Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA

Hostiuc, Mihaela:
 Carol Davila Univ Med & Pharm, Dept Internal Med, Bucharest, Romania

Househ, Mowafa:
 Hamad Bin Khalifa Univ, Coll Sci & Engn, Doha, Qatar

Ilesanmi, Olayinka Stephen:
 Univ Ibadan, Dept Community Med, Ibadan, Nigeria

 Univ Coll Hosp, Dept Community Med, Ibadan, Nigeria

Ilic, Milena D.:
 Univ Kragujevac, Dept Epidemiol, Kragujevac, Serbia

Irvani, Seyed Sina Naghibi:
 Shahid Beheshti Univ Med Sci, Res Inst Endocrine Sci, Tehran, Iran

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 Univ Sydney, Sydney Med Sch, Sydney, NSW, Australia

 Deakin Univ, Inst Phys Act & Nutr, Burwood, Vic, Australia

Jakovljevic, Mihajlo:
 Univ Kragujevac, Dept Global Hlth Econ & Policy, Kragujevac, Serbia

 IM Sechenov First Moscow State Med Univ, NA Semashko Dept Publ Hlth & Healthcare, Moscow, Russia

Jamal, Amr A.:
 King Saud Univ, Dept Family & Community Med, Riyadh, Saudi Arabia

Jha, Ravi Prakash:
 Baba Saheb Ambedkar Med Coll & Hosp, Dept Community Med, Delhi, India

 Banaras Hindu Univ, Dept Community Med, Varanasi, Uttar Pradesh, India

Jonas, Jost B.:
 Heidelberg Univ, Dept Ophthalmol, Mannheim, Germany

 Beijing Tongren Hosp, Beijing Inst Ophthalmol, Beijing, Peoples R China

Kabir, Zubair:
 Univ Coll Cork, Sch Publ Hlth, Cork, Ireland

Kasaeian, Amir:
 Iran Univ Med Sci, Pars Adv & Minimally Invas Med Manners Res Ctr, Tehran, Iran

 Univ Tehran Med Sci, Hematol Oncol & Stem Cell Transplantat Res Ctr, Tehran, Iran

Kasahun, Gebremicheal Gebreslassie:
 Aksum Univ, Sch Pharm, Aksum, Ethiopia

Kassa, Getachew Mullu:
 Debre Markos Univ, Coll Hlth Sci, Debre Markos, Ethiopia

Kefale, Adane Teshome:
 Debre Berhan Univ, Dept Pharm, Debre Berhan, Ethiopia

 Univ Tasmania, Sch Pharm, Hobart, Tas, Australia

Kengne, Andre Pascal:
 Med Res Council South Africa, Noncommunicable Dis Res Unit, Cape Town, South Africa

 Univ Cape Town, Dept Med, Cape Town, South Africa

Khader, Yousef Saleh:
 Jordan Univ Sci & Technol, Dept Publ Hlth, Irbid, Jordan

Khafaie, Morteza Abdullatif:
 Ahvaz Jundishapur Univ Med Sci, Social Determinants Hlth Res Ctr, Ahvaz, Iran

Khan, Ejaz Ahmad:
 Hlth Serv Acad, Dept Epidemiol & Biostat, Islamabad, Pakistan

Khan, Junaid:
 Int Inst Populat Sci, Dept Populat Studies, Mumbai, Maharashtra, India

Khubchandani, Jagdish:
 Ball State Univ, Dept Nutr & Hlth Sci, Muncie, IN 47306 USA

Kim, Young-Eun:
 Korea Univ, Dept Prevent Med, Seoul, South Korea

 Xiamen Univ Malaysia, Sch Tradit Chinese Med, Sepang, Malaysia

Kisa, Sezer:
 Oslo Metropolitan Univ, Dept Nursing & Hlth Promot, Oslo, Norway

Kisa, Adnan:
 Kristiania Univ Coll, Sch Hlth Sci, Oslo, Norway

 Tulane Univ, Global Community Hlth & Behav Sci, New Orleans, LA 70118 USA

Knibbs, Luke D.:
 Univ Queensland, Sch Publ Hlth, Herston, Qld, Australia

Komaki, Hamidreza:
 Hamadan Univ Med Sci, Neurophysiol Res Ctr, Hamadan, Iran

 Inst Res Fundamental Sci, Brain Engn Res Ctr, Tehran, Iran

Koul, Parvaiz A.:
 Sheri Kashmir Inst Med Sci, Dept Internal & Pulm Med, Srinagar, India

Koyanagi A:
 San Juan de Dios Sanitary Pk, CIBERSAM, St Boi De Llobregat, Spain

 Catalan Inst Res & Adv Studies ICREA, Barcelona, Spain

Kumar, G. Anil:
 Publ Hlth Fdn India, Gurugram, India

Lan, Qing:
 NCI, Div Canc Epidemiol & Genet, Rockville, MD USA

Lasrado, Savita:
 Father Muller Med Coll, Dept Otorhinolaryngol, Mangalore, India

Lauriola, Paolo:
 CNR, Inst Clin Physiol, Pisa, Italy

La Vecchia, Carlo:
 Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy

Tham Thi Le:
 Univ Maryland, Dept Pharmaceut Hlth Serv Res, Baltimore, MD 21201 USA

Leigh, James:
 Univ Sydney, Asbestos Dis Res Inst, Sydney, NSW, Australia

Levi, Miriam:
 USL Tuscany Ctr, Dept Prevent, Florence, Italy

 Univ Florence, Dept Hlth Sci, Florence, Italy

Li, Shanshan:
 Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia

Lopez, Alan D.:
 Reiner, Robert C

 Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia

Lotufo, Paulo A.:
 Univ Sao Paulo, Dept Med, Sao Paulo, Brazil

Madotto, Fabiana:
 IRCCS MultiMed, Value Based Healthcare Unit, Sesto San Giovanni, Italy

Mahotra, Narayan B.:
 Tribhuvan Univ, Dept Clin Physiol, Kathmandu, Nepal

Majdan, Marek:
 Trnava Univ, Dept Publ Hlth, Trnava, Slovakia

Majeed, Azeem:
 Imperial Coll London, Dept Primary Care & Publ Hlth, London, England

Malekzadeh, Reza:
 Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran

 Shiraz Univ Med Sci, Noncommunicable Dis Res Ctr, Shiraz, Iran

Mamun, Abdullah A.:
 Univ Queensland, Inst Social Sci Res, Indooroopilly, Qld, Australia

Manafi, Navid:
 Univ Manitoba, Ophthalmol Dept, Winnipeg, MB, Canada

 Iran Univ Med Sci, Dept Ophthalmol, Tehran, Iran

Manafi, Farzad:
 Univ Toronto, Joint Ctr Bioeth, Toronto, ON, Canada

Mantovani, Lorenzo Giovanni:
 IRCCS MultiMed, Value Based Healthcare Unit, Sesto San Giovanni, Italy

 Univ Milano Bicocca, Sch Med & Surg, Monza, Italy

Meharie, Birhanu Geta:
 Wollo Univ, Dept Pharm, Dessie, Ethiopia

Meles, Hagazi Gebre:
 Mekelle Univ, Mekelle, Ethiopia

Meles, Gebrekiros Gebremichael:
 Mekelle Univ, Sch Publ Hlth, Mekelle, Ethiopia

Menezes, Ritesh G.:
 Imam Abdulrahman Bin Faisal Univ, Forens Med Div, Dammam, Saudi Arabia

Mestrovic, Tomislav:
 Zora Profoz Polyclin, Clin Microbiol & Parasitol Unit, Zagreb, Croatia

 Univ North, Univ Ctr Varazdin, Varazhdin, Croatia

Miller, Ted R.:
 Pacific Inst Res Evaluat, Calverton, MD USA

 Curtin Univ, Sch Publ Hlth, Perth, WA, Australia

Mini, G. K.:
 Ananthapuri Hosp & Res Inst, Global Inst Publ Hlth, Trivandrum, Kerala, India

 Womens Social & Hlth Studies Fdn, Trivandrum, Kerala, India

Mirrakhimov, Erkin M.:
 Kyrgyz State Med Acad, Internal Med Programme, Bishkek, Kyrgyzstan

 Natl Ctr Cardiol & Internal Dis, Dept Atherosclerosis & Coronary Heart Dis, Bishkek, Kyrgyzstan

Moazen, Babak:
 Heidelberg Univ, HIGH, Heidelberg, Germany

 Frankfurt Univ Appl Sci, Inst Addict Res ISFF, Frankfurt, Germany

Mohammad, Karzan Abdulmuhsin:
 Salahaddin Univ Erbil, Dept Biol, Erbil, Iraq

Mohammed, Shafiu:
 Heidelberg Univ, HIGH, Heidelberg, Germany

 Ahmadu Bello Univ, Hlth Syst & Policy Res Unit, Zaria, Nigeria

Mohebi, Farnam:
 Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran

 Univ Tehran Med Sci, NIHR, Tehran, Iran

Mokdad, Ali H.:
 Reiner, Robert C

Molokhia, Mariam:
 Kings Coll London, Fac Life Sci & Med, London, England

Monasta, Lorenzo:
 Burlo Garofolo Inst Maternal & Child Hlth, Clin Epidemiol & Publ Hlth Res Unit, Trieste, Italy

Moradi, Masoud:
 Kermanshah Univ Med Sci, Res Ctr Environm Determinants Hlth, Kermanshah, Iran

Moradi, Ghobad:
 Kurdistan Univ Med Sci, Social Determinants Hlth Res Ctr, Sanandaj, Iran

 Kurdistan Univ Med Sci, Dept Epidemiol & Biostat, Sanandaj, Iran

Morawska, Lidia:
 Queensland Univ Technol, Int Lab Air Qual & Hlth, Brisbane, Qld, Australia

Mousavi, Seyyed Meysam:
 Univ Tehran Med Sci, Dept Hlth Policy Management & Econ, Tehran, Iran

Musa, Kamarul Imran:
 Sci Univ Malaysia, Sch Med Sci, Kubang Kerian, Malaysia

Mustafa, Ghulam:
 Childrens Hosp & Inst Child Hlth, Dept Pediat Med, Multan, Pakistan

 Inst M & Child Care, Dept Pediat & Pediat Pulmonol, Multan, Pakistan

Naderi, Mehdi:
 Kermanshah Univ Med Sci, Clin Res Dev Ctr, Kermanshah, Iran

Naghavi, Mohsen:
 Reiner, Robert C

Naik, Gurudatta:
 Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL 35294 USA

Nair, Sanjeev:
 Govt Med Coll Trivandrum, Dept Pulm Med, Trivandrum, Kerala, India

 Hlth Act People, Trivandrum, Kerala, India

Nangia, Vinay:
 Suraj Eye Inst, Nagpur, Maharashtra, India

Nansseu, Jobert Richie:
 Minist Publ Hlth, Dept Control Dis Epidem & Pandem, Yaounde, Cameroon

 Univ Yaounde I, Dept Publ Heath, Yaounde, Cameroon

Nazari, Javad:
 Arak Univ Med Sci, Dept Pediat, Arak, Iran

Ndwandwe, Duduzile Edith:
 South African Med Res Council, Cochrane South Africa, Cape Town, South Africa

Negoi, Ruxandra Irina:
 Carol Davila Univ Med & Pharm, Dept Anat & Embryol, Bucharest, Romania

 CardioAid, Bucharest, Romania

Trang Huyen Nguyen:
 Nguyen Tat Thanh Univ, Ctr Excellence Behav Med, Ho Chi Minh City, Vietnam

Cuong Tat Nguyen:
 Duy Tan Univ, Inst Global Hlth Innovat, Hanoi, Vietnam

Huong Lan Thi Nguyen:
 Duy Tan Univ, Inst Global Hlth Innovat, Hanoi, Vietnam

Nixon, Molly R.:
 Reiner, Robert C

Ofori-Asenso, Richard:
 Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia

 Univ Copenhagen, Dept Pharm, Copenhagen, Denmark

Ogbo, Felix Akpojene:
 Western Sydney Univ, Translat Hlth Res Inst, Sydney, NSW, Australia

Olagunju, Andrew T.:
 McMaster Univ, Dept Psychiat & Behav Neurosci, Hamilton, ON, Canada

 Univ Lagos, Dept Psychiat, Lagos, Nigeria

Olagunju, Tinuke O.:
 McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada

Oren, Eyal:
 Univ Washington, Seattle, WA 98195 USA

 San Diego State Univ, Grad Sch Publ Hlth, San Diego, CA 92182 USA

Ortiz, Justin R.:
 Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA

 Univ Maryland, Ctr Vaccine Dev, Baltimore, MD 21201 USA

Owolabi, Mayowa O.:
 Univ Ibadan, Dept Med, Ibadan, Nigeria

 Univ Coll Hosp, Dept Med, Ibadan, Nigeria

Pakhale, Smita:
 Ottawa Hosp Res Inst, Dept Med, Ottawa, ON, Canada

Pana, Adrian:
 Bucharest Univ Econ Studies, Dept Stat & Econometr, Bucharest, Romania

 Ctr Hlth Outcomes Evaluat, Dept Hlth Metr, Bucharest, Romania

Panda-Jonas, Songhomitra:
 Heidelberg Univ, Dept Ophthalmol, Heidelberg, Germany

Park, Eun-Kee:
 Kosin Univ, Dept Med Humanities & Social Med, Busan, South Korea

Hai Quang Pham:
 Duy Tan Univ, Inst Global Hlth Innovat, Hanoi, Vietnam

Postma, Maarten J.:
 Univ Groningen, Univ Med Ctr Groningen, Groningen, Netherlands

 Univ Groningen, Sch Econ & Business, Groningen, Netherlands

Pourjafar, Hadi:
 Maragheh Univ Med Sci, Dept Nutr & Food Sci, Maragheh, Iran

 Alborz Univ Med Sci, Dietary Supplements & Probiot Res Ctr, Karaj, Iran

Poustchi, Hossein:
 Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran

Radfar, Amir:
 Univ Cent Florida, Coll Med, Orlando, FL 32816 USA

Rafiei, Alireza:
 Mazandaran Univ Med Sci, Dept Immunol, Sari, Iran

 Mazandaran Univ Med Sci, Mol & Cell Biol Res Ctr, Sari, Iran

Rahim, Fakher:
 Univ Tehran Med Sci, Metabol & Genom Res Ctr, Tehran, Iran

 Ahvaz Jundishapur Univ Med Sci, Thalassemia & Hemoglobinopathy Res Ctr, Ahvaz, Iran

Rahman, Mohammad Hifz Ur:
 Federat Univ Australia, Sch Nursing & Healthcare Profess, Berwick, Vic, Australia

 La Trobe Univ, Sch Nursing & Midwifery, Melbourne, Vic, Australia

Rahman, Muhammad Aziz:
 Maharishi Markandeshwar Inst Med Sci & Res, Dept Community Med, Ambala, India

Rawaf, Salman:
 Imperial Coll London, Dept Primary Care & Publ Hlth, London, England

 Publ Hlth England, Acad Publ Hlth England, London, England

Rawaf, David Laith:
 Imperial Coll London, WHO Collaborating Ctr Publ Hlth Educ & Training, London, England

 Univ Coll London Hosp, London, England

Rawal, Lal:
 CQ Univ, Sch Hlth Med & Appl Sci, Sydney, NSW, Australia

Reitsma, Marissa Bettay:
 Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA

Roever, Leonardo:
 Univ Fed Uberlandia, Dept Clin Res, Uberlandia, MG, Brazil

Ronfani, Luca:
 Burlo Garofolo Inst Maternal & Child Hlth, Clin Epidemiol & Publ Hlth Res Unit, Trieste, Italy

Roro, Elias Merdassa:
 Wollega Univ, Dept Publ Hlth, Nekemte, Ethiopia

 Addis Ababa Univ, Sch Publ Hlth, Addis Ababa, Ethiopia

Roshandel, Gholamreza:
 Golestan Univ Med Sci, GRCGH, Gorgan, Golestan, Iran

Rudd, Kristina E.:
 Univ Pittsburgh, Dept Crit Care Med, Pittsburgh, PA USA

Sabde, Yogesh Damodar:
 Natl Inst Res Environm Hlth, Environm Epidemiol & Publ Hlth, Bhopal, India

Sabour, Siamak:
 Shahid Beheshti Univ Med Sci, Dept Epidemiol, Tehran, Iran

Saddik, Basema:
 Univ Sharjah, Dept Family & Community Med, Sharjah, U Arab Emirates

Safari, Saeed:
 Shahid Beheshti Univ Med Sci, Dept Emergency Med, Tehran, Iran

Saleem, Komal:
 Univ Manchester, Med & Human Sci Dept, Manchester, Lancs, England

 UCL, Div Med, London, England

Samy, Abdallah M.:
 Ain Shams Univ, Dept Entomol, Cairo, Egypt

Santric-Milicevic, Milena M.:
 Univ Belgrade, Fac Med, Belgrade, Serbia

 Univ Belgrade, Sch Publ Hlth & Hlth Management, Belgrade, Serbia

Jose, Bruno Piassi Sao:
 Univ Fed Minas Gerais, Dept Infect Dis & Trop Med, Belo Horizonte, MG, Brazil

Sartorius, Benn:
 Univ Washington, Sch Med, Dept Hlth Metr Sci, Seattle, WA USA

 London Sch Hyg & Trop Med, Fac Infect & Trop Dis, London, England

Satpathy, Maheswar:
 Utkal Univ, UGC Ctr Adv Study Psychol, Bhubaneswar, Odisha, India

 Udyam Global Assoc Sustainable Dev, Bhubaneswar, India

Savic, Miloje:
 GSK Biol, Wavre, Belgium

Sawhney, Monika:
 Univ N Carolina, Dept Publ Hlth Sci, Charlotte, NC USA

Sepanlou, Sadaf G.:
 Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran

 Shiraz Univ Med Sci, Noncommunicable Dis Res Ctr, Shiraz, Iran

Sheikh, Aziz:
 Harvard Univ, Div Gen Internal Med, Boston, MA 02115 USA

 Univ Edinburgh, Ctr Med Informat, Edinburgh, Midlothian, Scotland

Shigematsu, Mika:
 Natl Inst Infect Dis, Tokyo, Japan

Shirkoohi, Reza:
 Univ Tehran Med Sci, Canc Res Inst, Tehran, Iran

 Univ Tehran Med Sci, Canc Biol Res Ctr, Tehran, Iran

Si, Si:
 Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia

Siabani, Soraya:
 Kermanshah Univ Med Sci, Dept Hlth Educ & Hlth Promot, Kermanshah, Iran

 Univ Technol Sydney, Sch Hlth, Sydney, NSW, Australia

Singh, Virendra:
 Asthma Bhawan, Dept Pulm Med, Jaipur, Rajasthan, India

Singh, Jasvinder A.:
 Univ Alabama Birmingham, Sch Med, Birmingham, AL USA

 US Dept Vet Affairs, Med Serv, Birmingham, AL USA

Soljak, Michael:
 Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore, Singapore

 Imperial Coll London, Dept Primary Care & Publ Hlth, London, England

Somayaji, Ranjani:
 Univ Washington, Dept Med, Seattle, WA USA

 Univ Calgary, Dept Med, Calgary, AB, Canada

Soofi, Moslem:
 Kermanshah Univ Med Sci, Social Dev & Hlth Promot Res Ctr, Kermanshah, Iran

Soyiri, Ireneous N.:
 Univ Hull, Hull York Med Sch, Kingston Upon Hull, N Humberside, England

Tefera, Yonatal Mesfin:
 Wollo Univ, Dept Environm Hlth, Dessie, Ethiopia

 Univ Adelaide, Sch Publ Hlth, Adelaide, SA, Australia

Temsah, Mohamad-Hani:
 King Saud Univ, Pediat Intens Care Unit, Riyadh, Saudi Arabia

Tesfay, Berhe Etsay:
 Adigrat Univ, Dept Publ Hlth, Adigrat, Ethiopia

Thakur, Jarnail Singh:
 Post Grad Inst Med Educ & Res, Sch Publ Hlth, Chandigarh, India

Toma, Alemayehu Toma:
 Hawassa Univ, Dept Pharm, Hawassa, Ethiopia

Tortajada-Girbes, Miguel:
 Univ Hosp Doctor Peset, Pediat Dept, Valencia, Spain

 Univ Valencia, Dept Pediat Obstet & Gynecol, Valencia, Spain

Khanh Bao Tran:
 Univ Auckland, Mol Med & Pathol, Auckland, New Zealand

 Maurice Wilkins Ctr, Clin Hematol & Toxicol, Auckland, New Zealand

Bach Xuan Tran:
 Hanoi Med Univ, Dept Hlth Econ, Hanoi, Vietnam

Car, Lorainne Tudor:
 Nanyang Technol Univ, Lee Kong Chian Sch Med, Singapore, Singapore

Ullah, Irfan:
 Iqra Natl Univ, Dept Allied Hlth Sci, Peshawar, Pakistan

Vacante, Marco:
 Univ Catania, Dept Gen Surg & Med Surg Specialties, Catania, Italy

Valdez, Pascual R.:
 Argentine Soc Med, Buenos Aires, DF, Argentina

 Velez Sarsfield Hosp, Buenos Aires, DF, Argentina

van Boven, Job F. M.:
 Univ Groningen, Univ Med Ctr Groningen, Groningen, Netherlands

Vasankari, Tommi Juhani:
 UKK Inst, Tampere, Finland

Veisani, Yousef:
 Ilam Univ Med Sci, Psychosocial Injuries Res Ctr, Ilam, Iran

Violante, Francesco S.:
 Univ Bologna, Dept Med & Surg Sci, Bologna, Italy

 St Orsola Malpighi Hosp, Occupat Hlth Unit, Bologna, Italy

Wagner, Gregory R.:
 Harvard Univ, Dept Environm Hlth, Boston, MA 02115 USA

Westerman, Ronny:
 Fed Inst Populat Res, Competence Ctr Mortal Follow Up, German Natl Cohort, Wiesbaden, Germany

Wolfe, Charles D. A.:
 Kings Coll London, Sch Populat Hlth & Environm Sci, London, England

 Guys & St Thomas Hosp, NIHR Biomed Res Ctr, London, England

 Kings Coll London, NIHR Biomed Res Ctr, London, England

Wondafrash, Dawit Zewdu:
 Mekelle Univ, Dept Pharmacol & Toxicol, Mekelle, Ethiopia

 Addis Ababa Univ, Dept Pharmacol, Addis Ababa, Ethiopia

Wondmieneh, Adam Belay:
 Addis Ababa Univ, Sch Nursing & Midwifery, Addis Ababa, Ethiopia

 Wollo Univ, Dept Nursing, Dessie, Ethiopia

Yonemoto, Naohiro:
 Natl Ctr Neurol & Psychiat, Dept Neuropsychopharmaol, Kodaira, Tokyo, Japan

 Juntendo Univ, Dept Publ Hlth, Tokyo, Japan

Yoon, Seok-Jun:
 Korea Univ, Dept Prevent Med, Seoul, South Korea

Zaidi, Zoubida:
 Univ Ferhat Abbas Setif, Dept Med, Setif, Algeria

Zamani, Mohammad:
 Babol Univ Med Sci, Student Res Comm, Babol, Iran

Zar, Heather J.:
 Med Res Council South Africa, Unit Child & Adolescent Hlth, Cape Town, South Africa

 Univ Cape Town, Dept Paedt & Child Hlth, Cape Town, South Africa

Zhang, Yunquan:
 Wuhan Univ Sci & Technol, Sch Publ Hlth, Wuhan, Hubei, Peoples R China

 Wuhan Univ Sci & Technol, Hubei Prov Key Lab Occupat Hazard Identificat & C, Wuhan, Hubei, Peoples R China
ISSN: 22132600





Lancet Respiratory Medicine
Editorial
ELSEVIER SCI LTD, 125 London Wall, London EC2Y 5AS, ENGLAND, Reino Unido
Tipo de documento: Article
Volumen: 8 Número: 6
Páginas: 585-596
WOS Id: 000540618400031
ID de PubMed: 32526187
imagen Green Published, hybrid, Green Submitted

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