EDTA and NTA Effectively Tune the Mineralization of Calcium Phosphate from Bulk Aqueous Solution.
Por:
Hentrich D, Tauer K, Español-Pons M, Ginebra MP and Taubert A
Publicada:
13 dic 2017
Ahead of Print:
13 dic 2017
Resumen:
This study describes the effects of nitrilotriacetic acid (NTA) and ethylenediaminotetraacetic acid (EDTA) on the mineralization of calcium phosphate from bulk aqueous solution. Mineralization was performed between pH 6 and 9 and with NTA or EDTA concentrations of 0, 5, 10, and 15 mM. X-ray diffraction and infrared spectroscopy show that at low pH, mainly brushite precipitates and at higher pH, mostly hydroxyapatite forms. Both additives alter the morphology of the precipitates. Without additive, brushite precipitates as large plates. With NTA, the morphology changes to an unusual rod-like shape. With EDTA, the edges of the particles are rounded and disk-like particles form. Conductivity and pH measurements suggest that the final products form through several intermediate steps.
Filiaciones:
Hentrich D:
Institute of Chemistry, University of Potsdam, 14476 Potsdam, Germany.
Tauer K:
Max Planck Institute of Colloids and Interfaces, 14476 Potsdam, Germany.
Español-Pons M:
Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgy, Universitat Politècnica de Catalunya, Avinguda d' Eduard Maristany 10-14, 08019 Barcelona, Spain.
Barcelona Research Centre in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, 08019 Barcelona, Spain.
Open Access
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