S2k guidelines on diagnosis and treatment of linear IgA dermatosis initiated by the European Academy of Dermatology and Venereology
Por:
Caux, F, Patsatsi, A, Karakioulaki, M, Antiga, E, Baselga E, Borradori, L, Caproni, M, Cardones, AR, Chandran, NS, Dräger, S, Drenovska, K, Goebeler, M, Günther, C, Hofmann, SC, Ioannides, D, Joly, P, Marinovic, B, Mariotti, EB, Marzano, AV, Morel, KD, Murrell, DF, Prost, C, Sárdy, M, Setterfield, J, Skiljevic, D, Uzun, S, Vassileva, S, Zambruno, G and Schmidt, E
Publicada:
1 jun 2024
Ahead of Print:
1 feb 2024
Resumen:
Introduction: Linear IgA dermatosis (LAD) is a rare subepidermal autoimmune bullous disease (AIBD) defined by predominant or exclusive immune deposits of immunoglobulin A at the basement membrane zone of skin or mucous membranes. This disorder is a rare, clinically and immunologically heterogeneous disease occurring both in children and in adults. The aim of this project is to present the main clinical features of LAD, to propose a diagnostic algorithm and provide management guidelines based primarily on experts' opinion because of the lack of large methodologically sound clinical studies. Methods: These guidelines were initiated by the European Academy of Dermatology and Venereology (EADV) Task Force Autoimmune Bullous Diseases (AIBD). To achieve a broad consensus for these S2k consensus-based guidelines, a total of 29 experts from different countries, both European and non-European, including dermatologists, paediatric dermatologists and paediatricians were invited. All members of the guidelines committee agreed to develop consensus-based (S2k) guidelines. Prior to a first virtual consensus meeting, each of the invited authors elaborated a section of the present guidelines focusing on a selected topic, based on the relevant literature. All drafts were circulated among members of the writing group, and recommendations were discussed and voted during two hybrid consensus meetings. Results: The guidelines summarizes evidence-based and expert opinion-based recommendations (S2 level) on the diagnosis and treatment of LAD. Conclusion: These guidelines will support dermatologists to improve their knowledge on the diagnosis and management of LAD.
Filiaciones:
Caux, F:
Grp Hosp Paris Seine St Denis, AP HP, Dept Dermatol, Bobigny, France
Grp Hosp Paris Seine St Denis, AP HP, Referral Ctr Autoimmune Bullous Dis, Bobigny, France
Univ Paris 13, Bobigny, France
Patsatsi, A:
Aristotle Univ Thessaloniki, Sch Med, Papageorgiou Gen Hosp, Autoimmune Bullous Dis Unit,Dermatol Dept 2, Thessaloniki, Greece
Karakioulaki, M:
Univ Hosp Freiburg, Med Ctr, Dept Dermatol & Venereol, Freiburg, Germany
Antiga, E:
Univ Florence, Azienda USL Toscana Ctr, Dept Hlth Sci, Rare Dis Unit,Sect Dermatol, Florence, Italy
Baselga E:
Hosp St Joan Deu, Dept Dermatol, Barcelona, Spain
Borradori, L:
Univ Bern, Inselspital, Dept Dermatol, Bern, Switzerland
Caproni, M:
Univ Florence, Azienda USL Toscana Ctr, Dept Hlth Sci, Rare Dis Unit,Sect Dermatol, Florence, Italy
Cardones, AR:
Univ Kansas, Med Ctr, Dept Internal Med, Div Dermatol, Kansas City, KS USA
Chandran, NS:
Natl Univ Singapore Hosp, Dept Med, Div Dermatol, Singapore, Singapore
Dräger, S:
Univ Lubeck, Lubeck Inst Expt Dermatol LIED, Dept Dermatol, Lubeck, Germany
Drenovska, K:
Med Univ Sofia, Univ Hosp Alexandrovska, Dept Dermatol & Venereol, Sofia, Bulgaria
Goebeler, M:
Univ Hosp Wurzburg, Dept Dermatol Venereol & Allergol, Wurzburg, Germany
Günther, C:
Tech Univ Dresden, Univ Hosp, Dept Dermatol, Dresden, Germany
Hofmann, SC:
Univ Witten Herdecke, Helios Univ Hosp Wuppertal, Dept Dermatol Allergy & Dermatosurg, Wuppertal, Germany
Ioannides, D:
Aristotle Univ Thessaloniki, Hosp Skin & Venereal Dis, Sch Med, Dept Dermatol 1, Thessaloniki, Greece
Joly, P:
Normandie Univ, Rouen Univ Hosp, Dept Dermatol, INSERM 1234, Rouen, France
Marinovic, B:
Univ Zagreb, Univ Hosp Ctr Zagreb, Sch Med, Dept Dermatol & Venereol, Zagreb, Croatia
Mariotti, EB:
Univ Florence, Azienda USL Toscana Ctr, Dept Hlth Sci, Rare Dis Unit,Sect Dermatol, Florence, Italy
Marzano, AV:
Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dermatol Unit, Milan, Italy
Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy
Morel, KD:
Columbia Univ, Vagelos Coll Phys & Surg, Med Ctr, Dept Dermatol, New York, NY 10025 USA
Columbia Univ, Vagelos Coll Phys & Surg, Med Ctr, Dept Pediat, New York, NY USA
Murrell, DF:
Univ New South Wales, St George Hosp, Dept Dermatol, Sydney, NSW, Australia
Prost, C:
Grp Hosp Paris Seine St Denis, AP HP, Dept Dermatol, Bobigny, France
Grp Hosp Paris Seine St Denis, AP HP, Referral Ctr Autoimmune Bullous Dis, Bobigny, France
Univ Paris 13, Bobigny, France
Sárdy, M:
Semmelweis Univ, Dept Dermatol Venereol & Dermatooncol, Budapest, Hungary
LMU, Univ Hosp, Dept Dermatol & Allergy, Munich, Germany
Setterfield, J:
Guys & St Thomas NHS Fdn Trust, St Johns Inst Dermatol, London, England
Kings Coll London, Fac Dent Oral & Craniofacial Sci, Ctr Host Microbiome Interact, London, England
Skiljevic, D:
Univ Belgrade, Fac Med, Dept Dermatovenereol, Belgrade, Serbia
Uzun, S:
Akdeniz Univ, Fac Med, Dept Dermatol, Antalya, Turkiye
Vassileva, S:
Med Univ Sofia, Univ Hosp Alexandrovska, Dept Dermatol & Venereol, Sofia, Bulgaria
Zambruno, G:
IRCCS, Bambino Gesu Childrens Hosp, Translat Paediat & Clin Genet Res Div, Genodermatosis Unit, Rome, Italy
Schmidt, E:
Univ Lubeck, Lubeck Inst Expt Dermatol LIED, Dept Dermatol, Lubeck, Germany
Green Submitted, Bronze
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