Efficacy of the unified protocol for transdiagnostic treatment of comorbid emotional disorders in patients with ultra high risk for psychosis: Results of a randomized controlled trial
Por:
Peláez MT, López-Carrilero R, Espinosa V, Balsells S, Ochoa S and Osma J
Publicada:
15 dic 2024
Ahead of Print:
1 sep 2024
Resumen:
Background: The most common reason for help-seeking in ultra-high risk (UHR) for psychosis patients is comorbid symptoms, mainly anxiety and depression. However, psychological interventions are mainly focused on subthreshold psychotic symptoms. There is a growing push to include transdiagnostic therapies in specialized intervention teams for psychosis in young people. The Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders (UP) has demonstrated efficacy in emotional disorders, and its application has recently expanded to other pathologies such as borderline personality disorder (BPD) and bipolar disorder (BD). Methods: This pilot study was conducted with 36 patients with UHR for psychosis and symptoms of comorbid emotional disorders who were receiving treatment in an early intervention programme for psychosis. This is a randomised control trial (RCT) with two conditions: treatment as usual (TAU) with the group and online application of the UP (UP+TAU) (n = 18) and TAU (n = 18). Evaluations were conducted at baseline, after treatment, and at the three-month follow-up. Results: Comorbid anxiety and depression symptoms improved significantly in patients in the UP+TAU group compared to those in the TAU. Significant improvements in negative affect, emotional dysregulation, neuroticism, extraversion, functioning, and quality of life were also observed, and satisfaction with the intervention was high. Conclusions: UP may be an acceptable and effective intervention for the treatment of symptoms of comorbid emotional disorders in patients with UHR for psychosis.
Filiaciones:
Peláez MT:
Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat, Barcelona, Spain
Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain
Etiopatogènia i Tractament dels Trastorns Mentals Greus (MERITT), Institut de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain
Departamento de Psicología y Sociología, Universidad de Zaragoza, Zaragoza, Spain
López-Carrilero R:
Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat, Barcelona, Spain
Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain
Etiopatogènia i Tractament dels Trastorns Mentals Greus (MERITT), Institut de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain
Espinosa V:
Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat, Barcelona, Spain
Etiopatogènia i Tractament dels Trastorns Mentals Greus (MERITT), Institut de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain
Fundació de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Barcelona, Spain
Balsells S:
Fundació de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Barcelona, Spain
Ochoa S:
Parc Sanitari Sant Joan de Déu, 08830 Sant Boi de Llobregat, Barcelona, Spain
Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain
Etiopatogènia i Tractament dels Trastorns Mentals Greus (MERITT), Institut de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain
Osma J:
Departamento de Psicología y Sociología, Universidad de Zaragoza, Zaragoza, Spain
Instituto de Investigación Sanitaria de Aragón, Zaragoza, Spain.
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