Genomics yields biological and phenotypic insights into bipolar disorder.
Por:
O'Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, Agerbo E, Albani D, Alemany S, Alliey-Rodriguez N, Als TD, Andlauer TFM, Antoniou A, Ask H, Bass N, Bauer M, Beins EC, Bigdeli TB, Pedersen CB, Boks MP, Børte S, Rosa Bosch Munsó, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cabana-Domínguez J, Cairns MJ, Carpiniello B, Miguel Casas Brugué, Cervantes P, Chatzinakos C, Chen HC, Clarence T, Clarke TK, Claus I, Coombes B, Corfield EC, Cruceanu C, Cuellar-Barboza A, Czerski PM, Dafnas K, Dale AM, Dalkner N, Degenhardt F, DePaulo JR, Djurovic S, Drange OK, Escott-Price V, Fanous AH, Fellendorf FT, Ferrier IN, Forty L, Frank J, Frei O, Freimer NB, Fullard JF, Garnham J, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha TH, Hahn T, Haraldsson M, Hautzinger M, Havdahl A, Heilbronner U, Hellgren D, Herms S, Hickie IB, Hoffmann P, Holmans PA, Huang MC, Ikeda M, Jamain S, Johnson JS, Jonsson L, Kalman JL, Kamatani Y, Kennedy JL, Kim E, Kim J, Kittel-Schneider S, Knowles JA, Kogevinas M, Kranz TM, Krebs K, Kushner SA, Lavebratt C, Lawrence J, Leber M, Lee HJ, Liao C, Lucae S, Lundberg M, MacIntyre DJ, Maier W, Maihofer AX, Malaspina D, Manchia M, Maratou E, Martinsson L, Mattheisen M, McGregor NW, McInnis MG, McKay JD, Medeiros H, Meyer-Lindenberg A, Millischer V, Morris DW, Moutsatsou P, Mühleisen TW, O'Donovan C, Olsen CM, Panagiotaropoulou G, Papiol S, Pardiñas AF, Park HY, Perry A, Pfennig A, Pisanu C, Potash JB, Quested D, Rapaport MH, Regeer EJ, Rice JP, Rivera M, Schulte EC, Senner F, Shadrin A, Shilling PD, Sigurdsson E, Sindermann L, Sirignano L, Siskind D, Slaney C, Sloofman LG, Smeland OB, Smith DJ, Sobell JL, Soler Artigas M, Stein DJ, Stein F, Su MH, Sung H, Swiatkowska B, Terao C, Tesfaye M, Tesli M, Thorgeirsson TE, Thorp JG, Toma C, Tondo L, Tooney PA, Tsai SJ, Tsermpini EE, Vawter MP, Vedder H, Vreeker A, Walters JTR, Winsvold BS, Witt SH, Won HH, Ye R, Young AH, Zandi PP, Zillich L, Adolfsson R, Alda M, Alfredsson L, Backlund L, Baune BT, Bellivier F, Bengesser S, Berrettini WH, Biernacka JM, Boehnke M, Børglum AD, Breen G, Carr VJ, Catts S, Cichon S, Corvin A, Craddock N, Dannlowski U, Dikeos D, Etain B, Ferentinos P, Frye M, Fullerton JM, Gawlik M, Gershon ES, Goes FS, Green MJ, Grigoroiu-Serbanescu M, Hauser J, Henskens FA, Hjerling-Leffler J, Hougaard DM, Hveem K, Iwata N, Jones I, Jones LA, Kahn RS, Kelsoe JR, Kircher T, Kirov G, Kuo PH, Landén M, Leboyer M, Li QS, Lissowska J, Lochner C, Loughland C, Luykx JJ, Martin NG, Mathews CA, Mayoral F, McElroy SL, McIntosh AM, McMahon FJ, Medland SE, Melle I, Milani L, Mitchell PB, Morken G, Mors O, Mortensen PB, Müller-Myhsok B, Myers RM, Myung W, Neale BM, Nievergelt CM, Nordentoft M, Nöthen MM, Nurnberger JI, O'Donovan MC, Oedegaard KJ, Olsson T, Owen MJ, Paciga SA, Pantelis C, Pato CN, Pato MT, Patrinos GP, Pawlak JM, Ramos-Quiroga JA, Reif A, Reininghaus EZ, Ribasés M, Rietschel M, Ripke S, Rouleau GA, Roussos P, Saito T, Schall U, Schalling M, Schofield PR, Schulze TG, Scott LJ, Scott RJ, Serretti A, Smoller JW, Squassina A, Stahl EA, Stefansson H, Stefansson K, Stordal E, Streit F, Sullivan PF, Turecki G, Vaaler AE, Vieta E, Vincent JB, Waldman ID, Weickert CS, Weickert TW, Werge T, Whiteman DC, Zwart JA, Edenberg HJ, McQuillin A, Forstner AJ, Mullins N, Di Florio A, Ophoff RA and Andreassen OA
Publicada:
1 mar 2025
Ahead of Print:
22 ene 2025
Resumen:
Bipolar disorder is a leading contributor to the global burden of disease(1). Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown(2). We analysed data from participants of European, East Asian, African American and Latino ancestries (n = 158,036 cases with bipolar disorder, 2.8 million controls), combining clinical, community and self-reported samples. We identified 298 genome-wide significant loci in the multi-ancestry meta-analysis, a fourfold increase over previous findings(3), and identified an ancestry-specific association in the East Asian cohort. Integrating results from fine-mapping and other variant-to-gene mapping approaches identified 36 credible genes in the aetiology of bipolar disorder. Genes prioritized through fine-mapping were enriched for ultra-rare damaging missense and protein-truncating variations in cases with bipolar disorder(4), highlighting convergence of common and rare variant signals. We report differences in the genetic architecture of bipolar disorder depending on the source of patient ascertainment and on bipolar disorder subtype (type I or type II). Several analyses implicate specific cell types in the pathophysiology of bipolar disorder, including GABAergic interneurons and medium spiny neurons. Together, these analyses provide additional insights into the genetic architecture and biological underpinnings of bipolar disorder.
Filiaciones:
O'Connell KS:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Koromina M:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
van der Veen T:
Division of Psychiatry, University College London, London, UK
Boltz T:
Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
David FS:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany
Yang JMK:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Lin KH:
23andMe Inc., Sunnyvale, CA, USA
Wang X:
23andMe Inc., Sunnyvale, CA, USA
Coleman JRI:
Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK
NIHR Maudsley BRC, King's College London, London, UK
Mitchell BL:
Mental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
School of Biomedical Sciences and Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia
McGrouther CC:
New York University, New York, NY, USA
Rangan AV:
New York University, New York, NY, USA
Flatiron Institute, New York, NY, USA
Lind PA:
Mental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
School of Biomedical Sciences and Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia
School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia
Koch E:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Harder A:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Parker N:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Bendl J:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Adorjan K:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland
Agerbo E:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark
Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
Albani D:
Department of Neuroscience, Istituto Di Ricerche Farmacologiche Mario Negri IRCCS, Milano, Italy
Alemany S:
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d'Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Alliey-Rodriguez N:
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA
Northwestern University, Chicago, IL, USA
Als TD:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark
Department of Biomedicine-Human Genetics, Aarhus University, Aarhus, Denmark
Andlauer TFM:
Department of Neurology, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany
Antoniou A:
National and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece
Ask H:
PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway
PROMENTA Research Centre, Department of Psychology, University of Oslo, Oslo, Norway
Bass N:
Division of Psychiatry, University College London, London, UK
Bauer M:
Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Beins EC:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Bigdeli TB:
Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA
VA NY Harbor Healthcare System, Brooklyn, NY, USA
Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, NY, USA
Department of Epidemiology and Biostatistics, School of Public Health, SUNY Downstate Health Sciences University, Brooklyn, NY, USA
Pedersen CB:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark
Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
Boks MP:
Psychiatry, Brain Center UMC Utrecht, Utrecht, The Netherlands
Børte S:
Research and Communication Unit for Musculoskeletal Health, Division of Clinical Neuroscience, Oslo University Hospital, Ullevål, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Rosa Bosch Munsó:
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Programa SJD MIND Escoles, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain
Brum M:
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Brumpton BM:
K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Brunkhorst-Kanaan N:
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Budde M:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Bybjerg-Grauholm J:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
Byerley W:
Psychiatry, University of California San Francisco, San Francisco, CA, USA
Cabana-Domínguez J:
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d'Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Cairns MJ:
School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, New South Wales, Australia
Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton, New South Wales, Australia
Carpiniello B:
Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy
Miguel Casas Brugué:
Programa SJD MIND Escoles, Hospital Sant Joan de Déu, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain
Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
Fundació Privada d'Investigació Sant Pau (FISP), Barcelona, Spain
Cervantes P:
Department of Psychiatry, Mood Disorders Program, McGill University Health Center, Montreal, Québec, Canada
Chatzinakos C:
Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA
Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, NY, USA
Chen HC:
Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan
Department of Psychiatry, College of Medicine, National Taiwan University, Taipei, Taiwan
Clarence T:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Clarke TK:
Division of Psychiatry, University of Edinburgh, Edinburgh, UK
Claus I:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Coombes B:
Department of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN, USA
Corfield EC:
PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway
Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway
Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway
Cruceanu C:
Department of Psychiatry, Mood Disorders Program, McGill University Health Center, Montreal, Québec, Canada
Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Cuellar-Barboza A:
Department of Psychiatry, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
Czerski PM:
Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
Dafnas K:
National and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece
Dale AM:
Center for Multimodal Imaging and Genetics, Departments of Neurosciences, Radiology, and Psychiatry, University of California, San Diego, CA, USA
Dalkner N:
Division of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
Degenhardt F:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany
DePaulo JR:
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Djurovic S:
Department of Medical Genetics, Oslo University Hospital Ullevål, Oslo, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway
Drange OK:
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Department of Psychiatry, Sørlandet Hospital, Kristiansand, Norway
Escott-Price V:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Fanous AH:
Department of Psychiatry, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA
Carl T. Hayden Veterans Affairs Medical Center, Phoenix, AZ, USA
Banner-University Medical Center, Phoenix, AZ, USA
Fellendorf FT:
Division of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
Ferrier IN:
Academic Psychiatry, Newcastle University, Newcastle upon Tyne, UK
Forty L:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Frank J:
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Frei O:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Freimer NB:
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
Fullard JF:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Garnham J:
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
Gizer IR:
Department of Psychological Sciences, University of Missouri, Columbia, MO, USA
Gordon SD:
Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Gordon-Smith K:
Psychological Medicine, University of Worcester, Worcester, UK
Greenwood TA:
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Grove J:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Department of Biomedicine and the iSEQ Center, Aarhus University, Aarhus, Denmark
Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark
Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark
Guzman-Parra J:
Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain
Ha TH:
Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Hahn T:
Institute for Translational Psychiatry, University of Münster, Münster, Germany
Haraldsson M:
Faculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Landspitali University Hospital, Reykjavik, Iceland
Hautzinger M:
Department of Psychology, Eberhard Karls Universität Tübingen, Tubingen, Germany
Havdahl A:
PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway
PROMENTA Research Centre, Department of Psychology, University of Oslo, Oslo, Norway
Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway
Heilbronner U:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Hellgren D:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Herms S:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Department of Biomedicine, University of Basel, Basel, Switzerland
Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
Hickie IB:
Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia
Hoffmann P:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Department of Biomedicine, University of Basel, Basel, Switzerland
Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
Holmans PA:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Huang MC:
Department of Psychiatry, Taipei City Psychiatric Center, Taipei City Hospital, Taipei, Taiwan
Ikeda M:
Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan
Jamain S:
Université Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Créteil, France
Johnson JS:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Psychiatry, UNC Chapel Hill School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Jonsson L:
Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
Kalman JL:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
Kamatani Y:
Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
Kennedy JL:
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada
Kim E:
Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Department of Brain and Cognitive Sciences, Seoul National University College of Natural Sciences, Seoul, Republic of Korea
Kim J:
Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea
Kittel-Schneider S:
Department of Psychiatry and Neurobehavioral Science, University College Cork, Cork, Ireland
Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
Knowles JA:
Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA
Kogevinas M:
ISGlobal, Barcelona, Spain
Kranz TM:
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Krebs K:
Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia
Kushner SA:
Department of Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
Lavebratt C:
Translational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
Lawrence J:
Psychiatry, North East London NHS Foundation Trust, Ilford, UK
Leber M:
Clinic for Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany
Lee HJ:
Department of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea
Liao C:
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA
Lucae S:
Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
Lundberg M:
Translational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
MacIntyre DJ:
Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK
Maier W:
Department of Psychiatry and Psychotherapy, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Maihofer AX:
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Research/Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA
Malaspina D:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Manchia M:
Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy
Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy
Maratou E:
National and Kapodistrian University of Athens, Medical School, Clinical Biochemistry Laboratory, Attikon General Hospital, Athens, Greece
Martinsson L:
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Centre for Psychiatry Research, SLSO Region Stockholm, Stockholm, Sweden
Mattheisen M:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark
Department of Biomedicine-Human Genetics, Aarhus University, Aarhus, Denmark
Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
McGregor NW:
Human and Systems Genetics Working Group, Department of Genetics, Stellenbosch University, Stellenbosch, South Africa
McInnis MG:
Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
McKay JD:
Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France
Medeiros H:
Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY, USA
Meyer-Lindenberg A:
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
German Centre for Mental Health (DZPG), partner site Mannheim-Heidelberg-Ulm, Mannheim, Germany
Millischer V:
Translational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
Department of Psychiatry and Psychotherapy, Clinical Division of General Psychiatry, Medical University of Vienna, Vienna, Austria
Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria
Morris DW:
Centre for Neuroimaging and Cognitive Genomics (NICOG), School of Biological and Chemical Sciences, University of Galway, Galway, Ireland
Moutsatsou P:
National and Kapodistrian University of Athens, Medical School, Clinical Biochemistry Laboratory, Attikon General Hospital, Athens, Greece
Mühleisen TW:
Department of Biomedicine, University of Basel, Basel, Switzerland
Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany
O'Donovan C:
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
Olsen CM:
Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Panagiotaropoulou G:
Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, Germany
Papiol S:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Pardiñas AF:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Park HY:
Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Perry A:
Psychological Medicine, University of Worcester, Worcester, UK
Pfennig A:
Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Pisanu C:
Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy
Potash JB:
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Quested D:
Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
Rapaport MH:
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
Regeer EJ:
Outpatient Clinic for Bipolar Disorder, Altrecht, Utrecht, The Netherlands
Rice JP:
Department of Psychiatry, Washington University in Saint Louis, Saint Louis, MO, USA
Rivera M:
Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, University of Granada, Granada, Spain
Institute of Neurosciences 'Federico Olóriz', Biomedical Research Center (CIBM), University of Granada, Granada, Spain
Instituto de Investigación Biosanitaria Ibs.Granada, Granada, Spain
Schulte EC:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Psychotherapy, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Senner F:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany
Shadrin A:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
KG Jebsen Centre for Neurodevelopmental disorders, University of Oslo, Oslo, Norway
Shilling PD:
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Sigurdsson E:
Faculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Landspitali University Hospital, Reykjavik, Iceland
Sindermann L:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Sirignano L:
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Siskind D:
Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia
Slaney C:
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
Sloofman LG:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Smeland OB:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Smith DJ:
Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
Sobell JL:
Psychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, CA, USA
Soler Artigas M:
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d'Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Department of Genetics, Microbiology, and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain
Stein DJ:
SAMRC Unit on Risk and Resilience in Mental Disorders, Dept of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa
Stein F:
Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany
Su MH:
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA
Sung H:
Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA
Swiatkowska B:
Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland
Terao C:
Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
Tesfaye M:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway
Tesli M:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway
Thorgeirsson TE:
deCODE Genetics/Amgen, Reykjavik, Iceland
Thorp JG:
Mental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Toma C:
Neuroscience Research Australia, Sydney, New South Wales, Australia
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Centro de Biología Molecular Severo Ochoa, Universidad Autónoma de Madrid and CSIC, Madrid, Spain
Tondo L:
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Tooney PA:
School of Biomedical Science and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia
Tsai SJ:
Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan
Division of Psychiatry, National Yang Ming Chiao Tung University, Taipei, Taiwan
Tsermpini EE:
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
Vawter MP:
Department of Psychiatry and Human Behavior, School of Medicine, University of California, Irvine, CA, USA
Vedder H:
Psychiatry, Psychiatrisches Zentrum Nordbaden, Wiesloch, Germany
Vreeker A:
Psychiatry, Brain Center UMC Utrecht, Utrecht, The Netherlands
Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC Sophia Children Hospital, Erasmus University, Rotterdam, The Netherlands
Department of Psychology Education and Child Studies, Erasmus School of Social and Behavioral Sciences, Erasmus University Rotterdam, Rotterdam, The Netherlands
Walters JTR:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Winsvold BS:
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway
Department of Neurology, Oslo University Hospital, Oslo, Norway
Witt SH:
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Won HH:
Samsung Advanced Institute for Health Sciences and Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea
Samsung Genome Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
Ye R:
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA
Young AH:
Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Kent, UK
Zandi PP:
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Zillich L:
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Adolfsson R:
Department of Clinical Sciences, Psychiatry, Umeå University Medical Faculty, Umeå, Sweden
Alda M:
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
National Institute of Mental Health, Klecany, Czech Republic
Alfredsson L:
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Backlund L:
Translational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
Baune BT:
Department of Psychiatry, University of Münster, Münster, Germany
Department of Psychiatry, Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia
The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia
Bellivier F:
Université Paris Cité, INSERM, Optimisation Thérapeutique en Neuropsychopharmacologie, UMRS-1144, Paris, France
APHP Nord, DMU Neurosciences, GHU Saint Louis-Lariboisière-Fernand Widal, Département de Psychiatrie et de Médecine Addictologique, Paris, France
Bengesser S:
Division of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
Berrettini WH:
Psychiatry, University of Pennsylvania, Philadelphia, PA, USA
Biernacka JM:
Department of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN, USA
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
Boehnke M:
Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA
Børglum AD:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Department of Biomedicine and the iSEQ Center, Aarhus University, Aarhus, Denmark
Center for Genomics and Personalized Medicine, CGPM, Aarhus, Denmark
Breen G:
Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK
NIHR Maudsley BRC, King's College London, London, UK
Carr VJ:
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Catts S:
University of Queensland, Brisbane, Queensland, Australia
Cichon S:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Department of Biomedicine, University of Basel, Basel, Switzerland
Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany
Corvin A:
Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland
Craddock N:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Dannlowski U:
Institute for Translational Psychiatry, University of Münster, Münster, Germany
Dikeos D:
National and Kapodistrian University of Athens, 1st Department of Psychiatry, Eginition Hospital, Athens, Greece
Etain B:
Université Paris Cité, INSERM, Optimisation Thérapeutique en Neuropsychopharmacologie, UMRS-1144, Paris, France
APHP Nord, DMU Neurosciences, GHU Saint Louis-Lariboisière-Fernand Widal, Département de Psychiatrie et de Médecine Addictologique, Paris, France
Ferentinos P:
Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK
National and Kapodistrian University of Athens, 2nd Department of Psychiatry, Attikon General Hospital, Athens, Greece
Frye M:
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
Fullerton JM:
Neuroscience Research Australia, Sydney, New South Wales, Australia
School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Gawlik M:
Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany
Gershon ES:
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA
Department of Human Genetics, University of Chicago, Chicago, IL, USA
Goes FS:
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Green MJ:
Neuroscience Research Australia, Sydney, New South Wales, Australia
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Grigoroiu-Serbanescu M:
Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania
Hauser J:
Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
Henskens FA:
School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia
Hjerling-Leffler J:
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
Hougaard DM:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
Hveem K:
K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Iwata N:
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan
Jones I:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Jones LA:
Psychological Medicine, University of Worcester, Worcester, UK
Kahn RS:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Psychiatry, Brain Center UMC Utrecht, Utrecht, The Netherlands
Kelsoe JR:
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Kircher T:
Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany
Kirov G:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Kuo PH:
Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan
Department of Public Health and Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Landén M:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
Leboyer M:
Université Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Créteil, France
Li QS:
Neuroscience Therapeutic Area, Janssen Research and Development, Titusville, NJ, USA
JRD Data Science, Janssen Research and Development, Titusville, NJ, USA
Lissowska J:
Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
Lochner C:
SA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry, Stellenbosch University, Stellenbosch, South Africa
Loughland C:
University of Newcastle, Newcastle, New South Wales, Australia
Luykx JJ:
Department of Psychiatry, Amsterdam University Medical Center, Amsterdam, The Netherlands
Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands
Martin NG:
Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
School of Psychology, The University of Queensland, Brisbane, Queensland, Australia
Mathews CA:
Department of Psychiatry, University of Florida, Gainesville, FL, USA
Mayoral F:
Mental Health Department, University Regional Hospital, Biomedicine Institute (IBIMA), Málaga, Spain
McElroy SL:
Research Institute, Lindner Center of HOPE, Mason, OH, USA
McIntosh AM:
Division of Psychiatry, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK
McMahon FJ:
Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD, USA
Medland SE:
Mental Health and Neuroscience, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
School of Psychology, The University of Queensland, Brisbane, Queensland, Australia
School of Psychology and Counselling, Queensland University of Technology, Brisbane, Queensland, Australia
Melle I:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Division of Mental Health and Addiction, University of Oslo, Institute of Clinical Medicine, Oslo, Norway
Milani L:
Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia
Mitchell PB:
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Morken G:
Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
Psychiatry, St Olavs University Hospital, Trondheim, Norway
Mors O:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Risskov, Denmark
Mortensen PB:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
NCRR and CIRRAU, Aarhus BSS, Aarhus University, Aarhus, Denmark
Müller-Myhsok B:
Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
University of Liverpool, Liverpool, UK
Myers RM:
HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA
Myung W:
Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul, Republic of Korea
Neale BM:
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA
Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
Nievergelt CM:
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Research/Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA
Nordentoft M:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark
Nöthen MM:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Nurnberger JI:
Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA
O'Donovan MC:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Oedegaard KJ:
Division of Psychiatry, Haukeland Universitetssjukehus, Bergen, Norway
Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway
Olsson T:
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Center for Molecular Medicine, Stockholm, Sweden
Owen MJ:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Paciga SA:
Human Genetics and Computational Biomedicine, Pfizer Global Research and Development, Groton, CT, USA
Pantelis C:
The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
Monash Institute of Pharmaceutical Sciences (MIPS), Monash University, Parkville, Victoria, Australia
Pato CN:
Rutgers Health, Rutgers University, Piscataway, NJ, USA
Pato MT:
Rutgers Health, Rutgers University, Piscataway, NJ, USA
Patrinos GP:
University of Patras, School of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, Patras, Greece
Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates
Zayed Center for Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates
Department of Pathology, Faculty of Medicine and Health Sciences, Clinical Bioinformatics Unit, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
Pawlak JM:
Department of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
Ramos-Quiroga JA:
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d'Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
Reif A:
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Reininghaus EZ:
Division of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria
Ribasés M:
Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall d'Hebron Research Institut (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Department of Genetics, Microbiology, and Statistics, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain
Rietschel M:
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Ripke S:
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA
Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, Germany
Rouleau GA:
Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal, Québec, Canada
Montreal Neurological Institute and Hospital, McGill University, Montréal, Québec, Canada
Roussos P:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY, USA
Saito T:
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan
Schall U:
Centre for Brain and Mental Health Research, The University of Newcastle, Newcastle, New South Wales, Australia
Hunter Medical Research Institute, New Lambtion Heights, New South Wales, Australia
Schalling M:
Translational Psychiatry, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
Schofield PR:
Neuroscience Research Australia, Sydney, New South Wales, Australia
School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Schulze TG:
Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany
Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA
Scott LJ:
Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA
Scott RJ:
The School of Biomedical Sciences and Pharmacy, Faculty of Medicine, Health and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia
Cancer Detection and Therapies Program, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia
Serretti A:
Department of Medicine and Surgery, Kore University of Enna, Enna, Italy
Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy
Oasi Research Institute-IRCCS, Troina, Italy
Smoller JW:
Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA
Squassina A:
Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy
Stahl EA:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
Stefansson H:
deCODE Genetics/Amgen, Reykjavik, Iceland
Stefansson K:
deCODE Genetics/Amgen, Reykjavik, Iceland
Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Stordal E:
Department of Psychiatry, Hospital Namsos, Namsos, Norway
Department of Neuroscience, Norges Teknisk Naturvitenskapelige Universitet Fakultet for naturvitenskap og teknologi, Trondheim, Norway
Streit F:
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
Hector Institute for Artificial Intelligence in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Sullivan PF:
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Turecki G:
Department of Psychiatry, McGill University, Montreal, Québec, Canada
Vaaler AE:
Department of Psychiatry, Sankt Olavs Hospital Universitetssykehuset i Trondheim, Trondheim, Norway
Vieta E:
Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain
Vincent JB:
Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Waldman ID:
Department of Psychology, Emory University, Atlanta, GA, USA
Weickert CS:
Neuroscience Research Australia, Sydney, New South Wales, Australia
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Department of Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA
Weickert TW:
Neuroscience Research Australia, Sydney, New South Wales, Australia
Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia
Department of Neuroscience, SUNY Upstate Medical University, Syracuse, NY, USA
Werge T:
iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Center for GeoGenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark
Whiteman DC:
Population Health, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia
Zwart JA:
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway
Edenberg HJ:
Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA
McQuillin A:
Division of Psychiatry, University College London, London, UK
Forstner AJ:
Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany
Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany
Centre for Human Genetics, University of Marburg, Marburg, Germany
Mullins N:
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Di Florio A:
Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Ophoff RA:
Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA
Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
Andreassen OA:
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Center for Precision Psychiatry, University of Oslo, Oslo, Norway
Emory Univ, Dept Psychol, Atlanta, GA 30322 USA
Green Submitted
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