The association between physical multimorbidity and fall-related injury among adults aged = 50 years from low- and middle-income countries
Por:
Smith L, López Sánchez GF, Shin JI, Hans Oh, Kostev K, Tully MA, Barnett Y, Butler LT, Veronese N, Soysal P, Jacob L. and Koyanagi A
Publicada:
1 dic 2025
Ahead of Print:
20 mar 2025
Resumen:
Studies from high-income countries have shown that multimorbidity is associated with increased fall risk among older adults. However, studies specifically on this topic from low- and middle-income counties (LMICs) are lacking. Thus, we aimed to assess this association among adults aged >= 50 years from six LMICs.Cross-sectional, community-based data from the Study on Global Ageing and Adult Health (SAGE) were analyzed. Eleven chronic physical conditions were assessed. The presence of past 12-month fall-related injury was ascertained through self-reported information. Multivariable logistic regression and mediation analysis was conducted to assess the association between multimorbidity and fall-related injury.Data on 34,129 adults aged >= 50 years [mean (SD) age 62.4 (16.0) years; males 48.0%] were analyzed. Overall, compared to having no chronic conditions, having 2, 3, and >= 4 chronic conditions were significantly associated with 1.67 (95%CI = 1.21-2.30), 2.64 (95%CI = 1.89-3.68), and 3.67 (95%CI = 2.42-5.57) times higher odds for fall-related injury. The association between multimorbidity (i.e., >= 2 chronic conditions) and fall-related injury was mainly explained by pain/discomfort (mediated% 39.7%), mobility (34.1%), sleep/energy (24.2%), and cognition (13.0%).Older adults with multimorbidity in LMICs are at increased odds for fall-related injury. Targeting the identified potential mediators among those with multimorbidity may reduce fall risk in this population.
Filiaciones:
Smith L:
Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK
López Sánchez GF:
Division of Preventive Medicine and Public Health, Department of Public Health Sciences, School of Medicine, University of Murcia, Murcia, Spain
Shin JI:
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea
Institute of Convergence Science, Severance Underwood Meta-Research Center, Yonsei University, Seoul, Republic of Korea
Hans Oh:
Suzanne Dworak Peck School of Social Work, University of Southern California, Los Angeles, CA, USA
Kostev K:
University Clinic of Marburg, Marburg, Germany
Tully MA:
School of Medicine, Ulster University, Londonderry, Northern Ireland, UK
Barnett Y:
Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK
Butler LT:
Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge, UK
Veronese N:
Saint Camillus International University of Health Sciences, Faculty of Medicine, Rome, Italy
Soysal P:
Department of geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey
Jacob L.:
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain
Assistance Publique - Hôpitaux de Paris (AP-HP) / Université Paris Cité, Lariboisière - Fernand Widal Hospital, Department of Physical Medicine and Rehabilitation, Paris, France
Inserm / Université Paris Cité, UMR 1153, CRESS, Epidemiology of Ageing and Neurodegenerative Diseases (EpiAgeing), Paris, France
Koyanagi A:
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Dr. Antoni Pujadas, Sant Boi de Llobregat, Barcelona, Spain
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