Risk factors for suicide behaviors in the observational schizophrenia outpatient health outcomes (SOHO) study
Por:
Brugnoli R, Novick D, Haro JM, Rossi A, Bortolomasi M, Frediani S and Borgherini G
Publicada:
19 jul 2012
Categoría:
Psychiatry and Mental Health
Resumen:
Background: To identify risk factors for suicide using data from a
large, 3-year, multinational follow-up study of schizophrenia (SOHO
study).
Methods: Baseline characteristics of 8,871 adult patients with
schizophrenia were included in a logistic regression post-hoc analysis
comparing patients who attempted and/or committed suicide during the
study with those who did not.
Results: 384 (4.3%) patients attempted or committed suicide. Completed
suicides were 27 (0.3%). The significant risk factors for suicide
behaviors were previous suicidality, depressive symptoms,
prolactin-related adverse events, male gender and history of
hospitalization for schizophrenia.
Conclusions: In view of the observational design of the study and the
post-hoc nature of the analysis, the identified risk factors should be
confirmed by ad-hoc specifically designed studies.
Open Access
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