Pathway-Specific Polygenic Scores for Predicting Clinical Lithium Treatment Response in Patients With Bipolar Disorder

Por: Sharew NT, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Fullerton JM, Hou L, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Hasler R, Richard-Lepouriel H, Perroud N, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Marie-Claire C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Del Zompo M, DePaulo JR, Étain B, Jamain S, Falkai P, Forstner AJ, Frisen L, Frye MA, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Fallgatter AJ, Stegmaier S, Ethofer T, Biere S, Petrova K, Schuster C, Adorjan K, Budde M, Heilbronner M, Kalman JL, Kohshour MO, Reich-Erkelenz D, Schaupp SK, Schulte EC, Senner F, Vogl T, Anghelescu IG, Arolt V, Dannlowski U, Dietrich DE, Figge C, Jäger M, Lang FU, Juckel G, Konrad C, Reimer J, Schmauß M, Schmitt A, Spitzer C, von Hagen M, Wiltfang J, Zimmermann J, Andlauer TFM, Fischer A, Bermpohl F, Ritter P, Matura S, Gryaznova A, Falkenberg I, Yildiz C, Kircher T, Schmidt J, Koch M, Gade K, Trost S, Haussleiter IS, Lambert M, Rohenkohl AC, Kraft V, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Ferensztajn-Rochowiak E, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Millischer V, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Pfennig A, Pisanu C, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Viswanath B, Witt SH, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT, Schubert KO and Amare AT

---

Publicada: 1 sep 2025 Ahead of Print: 1 ago 2025

---

---

Filiaciones:
Sharew NT:
 Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia

 Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia

Clark SR:
 Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia

Papiol S:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University Munich, Munich, Germany

Heilbronner U:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Degenhardt F:
 Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

 Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University of Duisburg-Essen, Rheinische Kliniken, Essen, Germany

Fullerton JM:
 Neuroscience Research Australia, Sydney, New South Wales, Australia

 School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia

Hou L:
 Intramural Research Program, National Institute of Mental Health, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland

Shekhtman T:
 Department of Psychiatry, University of California San Diego, San Diego, California

Adli M:
 Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany

Akula N:
 Intramural Research Program, National Institute of Mental Health, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland

Akiyama K:
 Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Tochigi, Japan

Ardau R:
 Unit of Clinical Pharmacology, Hospital University Agency of Cagliari, Cagliari, Italy

Arias B:
 Unitat de Zoologia i Antropologia Biològica (Dpt. Biologia Evolutiva, Ecologia i Ciències Ambientals), Facultat de Biologia and Institut de Biomedicina, University of Barcelona, CIBERSAM, Barcelona, Spain

Hasler R:
 Department of Psychiatry, Mood Disorders Unit, HUG - Geneva University Hospitals, Geneva, Switzerland

Richard-Lepouriel H:
 Department of Psychiatry, Mood Disorders Unit, HUG - Geneva University Hospitals, Geneva, Switzerland

Perroud N:
 Department of Psychiatry, Mood Disorders Unit, HUG - Geneva University Hospitals, Geneva, Switzerland

Backlund L:
 Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

 Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

Bhattacharjee AK:
 Department of Psychiatry, University of California San Diego, San Diego, California

Bellivier F:
 Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-S 1144, Université Paris Cité, Département de Psychiatrie et de Médecine Addictologique, L'Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-F.Widal, Paris, France

Benabarre A:
 Bipolar and Depressive Disorders Program, Institute of Neuroscience, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain

Bengesser S:
 Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria

Biernacka JM:
 Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota

 Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota

Birner A:
 Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria

Marie-Claire C:
 Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-S 1144, Université Paris Cité, Département de Psychiatrie et de Médecine Addictologique, L'Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-F.Widal, Paris, France

 Université Paris Cité, Inserm, Optimisation Thérapeutique en Neuropsychopharmacologie, Paris, France

Cervantes P:
 Neuromodulation Unit, McGill University Health Centre, Montreal, Quebec, Canada

Chen HC:
 Department of Psychiatry & Center of Sleep Disorders, National Taiwan University Hospital, Taipei, Taiwan

Chillotti C:
 Unit of Clinical Pharmacology, Hospital University Agency of Cagliari, Cagliari, Italy

Cichon S:
 Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland

 Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland

 Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany

Cruceanu C:
 Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada

Czerski PM:
 Psychiatric Genetic Unit, Poznan University of Medical Sciences, Poznan, Poland

Dalkner N:
 Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria

Del Zompo M:
 Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

DePaulo JR:
 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

Étain B:
 Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-S 1144, Université Paris Cité, Département de Psychiatrie et de Médecine Addictologique, L'Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-F.Widal, Paris, France

Jamain S:
 Inserm U955, Fondation FondaMental, Translational Psychiatry Laboratory, Créteil, France

Falkai P:
 Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University Munich, Munich, Germany

 Max Planck Institute of Psychiatry, Munich, Germany

Forstner AJ:
 Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

 Institute of Neuroscience and Medicine, Research Center Jülich, Jülich, Germany

Frisen L:
 Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

 Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden

Frye MA:
 Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota

Gard S:
 Pôle de Psychiatrie Générale Universitaire, Hôpital Charles Perrens, Bordeaux, France

Garnham JS:
 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada

Goes FS:
 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

Grigoroiu-Serbanescu M:
 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada

Fallgatter AJ:
 Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania

Stegmaier S:
 University Department of Psychiatry and Psychotherapy Tuebingen, University of Tübingen, Tübingen, Germany

Ethofer T:
 Department of General Psychiatry, University of Tübingen, Tübingen, Germany

 Department of Biomedical Resonance, University of Tübingen, Tübingen, Germany

Biere S:
 Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Frankfurt, Goethe University, Frankfurt, Germany

Petrova K:
 Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Frankfurt, Goethe University, Frankfurt, Germany

Schuster C:
 Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Frankfurt, Goethe University, Frankfurt, Germany

Adorjan K:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Department of Psychiatry and Psychotherapie, University of Bern, Bern, Switzerland

Budde M:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Heilbronner M:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Kalman JL:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University Munich, Munich, Germany

Kohshour MO:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Reich-Erkelenz D:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Schaupp SK:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Schulte EC:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University Munich, Munich, Germany

Senner F:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University Munich, Munich, Germany

Vogl T:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Anghelescu IG:
 Department of Psychiatry and Psychotherapy, Mental Health Institute Berlin, Berlin, Germany

Arolt V:
 Institute for Translational Psychiatry, University of Münster, Münster, Germany

Dannlowski U:
 Institute for Translational Psychiatry, University of Münster, Münster, Germany

Dietrich DE:
 AMEOS Clinical Center Hildesheim, Hildesheim, Germany

 Center for Systems Neuroscience, Hannover, Germany

Figge C:
 Karl-Jaspers Clinic, European Medical School Oldenburg-Groningen, Oldenburg, Germany

Jäger M:
 Department of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, Günzburg, Germany

Lang FU:
 Department of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, Günzburg, Germany

Juckel G:
 Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Bochum, Germany

Konrad C:
 Department of Psychiatry and Psychotherapy, Agaplesion Diakonieklinikum, Rotenburg, Germany

Reimer J:
 Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

 Department of Psychiatry, Health North Hospital Group, Bremen, Germany

Schmauß M:
 Department of Psychiatry and Psychotherapy, Bezirkskrankenhaus Augsburg, Augsburg, Germany

Schmitt A:
 Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University Munich, Munich, Germany

 Laboratory of Neuroscience, Institute of Psychiatry, University of Sao Paulo, São Paulo, Brazil

Spitzer C:
 Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Rostock, Germany

von Hagen M:
 Clinic for Psychiatry and Psychotherapy, Clinical Center Werra-Meißner, Eschwege, Germany

Wiltfang J:
 Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany

 German Center for Neurodegenerative Diseases, University of Göttingen, Göttingen, Germany

Zimmermann J:
 Psychiatrieverbund Oldenburger Land GmbH, Karl-Jaspers-Klinik, Bad Zwischenahn, Germany

Andlauer TFM:
 Department of Neurology, University Hospital Rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany

Fischer A:
 German Center for Neurodegenerative Diseases, University of Göttingen, Göttingen, Germany

Bermpohl F:
 Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany

Ritter P:
 Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany

Matura S:
 Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital of Frankfurt, Goethe University, Frankfurt, Germany

Gryaznova A:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

Falkenberg I:
 Department of Psychiatry and Psychotherapy, Philipps-University, Marburg, Germany

Yildiz C:
 Department of Psychiatry and Psychotherapy, Philipps-University, Marburg, Germany

Kircher T:
 Department of Psychiatry and Psychotherapy, Philipps-University, Marburg, Germany

Schmidt J:
 Institute for Medical Informatics, University Medical Center Göttingen, Göttingen, Germany

Koch M:
 Institute for Medical Informatics, University Medical Center Göttingen, Göttingen, Germany

Gade K:
 Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany

Trost S:
 Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany

Haussleiter IS:
 Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Bochum, Germany

Lambert M:
 Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Rohenkohl AC:
 Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Kraft V:
 Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Grof P:
 Mood Disorders Center of Ottawa, Ottawa, Ontario, Canada

Hashimoto R:
 Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan

Hauser J:
 Psychiatric Genetic Unit, Poznan University of Medical Sciences, Poznan, Poland

Herms S:
 Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

 Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland

Hoffmann P:
 Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

 Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland

Jiménez E:
 Bipolar and Depressive Disorders Program, Institute of Neuroscience, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain

Kahn JP:
 Service de Psychiatrie et Psychologie Clinique, Centre Psychothérapique de Nancy, Université de Lorraine, Nancy, France

Kassem L:
 Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany

Kuo PH:
 Department of Public Health & Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan

Kato T:
 Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, Saitama, Saitama, Japan

Kelsoe J:
 Department of Psychiatry, University of California San Diego, San Diego, California

Kittel-Schneider S:
 Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany

 Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, University Hospital of Würzburg, Würzburg, Germany

Ferensztajn-Rochowiak E:
 Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland

König B:
 Department of Psychiatry and Psychotherapeutic Medicine, Landesklinikum Neunkirchen, Neunkirchen, Austria

Kusumi I:
 Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan

Laje G:
 Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany

Landén M:
 Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the Gothenburg University, Gothenburg, Sweden

 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Lavebratt C:
 Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

 Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

Leboyer M:
 Inserm U955, Translational Psychiatry Laboratory, Université Paris-Est-Créteil, Department of Psychiatry and Addictology of Mondor University Hospital, AP-HP, Fondation FondaMental, Créteil, France

Leckband SG:
 Office of Mental Health, VA San Diego Healthcare System, San Diego, California

Tortorella A:
 Department of Psychiatry, University of Perugia, Perugia, Italy

Manchia M:
 Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

 Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada

Martinsson L:
 Department of Clinical Neurosciences, Karolinska Institute, Stockholm, Sweden

McCarthy MJ:
 Department of Psychiatry, University of California San Diego, San Diego, California

 Department of Psychiatry, VA San Diego Healthcare System, San Diego, California

McElroy S:
 Department of Psychiatry, Lindner Center of Hope, University of Cincinnati, Mason, Ohio

Colom F:
 Mental Health Research Group, Hospital del Mar Medical Research Institute, Barcelona, Catalonia, Spain

 Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona, Barcelona, Spain

Millischer V:
 Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

 Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

 Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

:
 Department of Genetics, Microbiology and Statistics, Faculty of Biology, University of Barcelona, Barcelona, Spain

 CIBERSAM, Instituto de Salud Carlos III, Madrid, Spain

 Institut de Biomedicina de la Universitat de Barcelona, Barcelona, Spain

 Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain

Mondimore FM:
 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

Monteleone P:
 Neurosciences Section, Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy

 Department of Psychiatry, University of Campania "Luigi Vanvitelli", Naples, Italy

Nievergelt CM:
 Department of Psychiatry, University of California San Diego, San Diego, California

Nöthen MM:
 Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

Novák T:
 National Institute of Mental Health, Klecany, Czechia

O'Donovan C:
 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada

Ozaki N:
 Department of Psychiatry & Department of Child and Adolescent Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan

Pfennig A:
 Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany

Pisanu C:
 Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

Potash JB:
 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

Reif A:
 Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany

Reininghaus E:
 Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria

Rouleau GA:
 Montreal Neurological Institute and Hospital, McGill University, Montréal, Québec, Canada

Rybakowski JK:
 Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland

Schalling M:
 Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

 Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden

Schofield PR:
 Neuroscience Research Australia, Sydney, New South Wales, Australia

 School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia

Schweizer BW:
 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

Severino G:
 Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

Shilling PD:
 Department of Psychiatry, University of California San Diego, San Diego, California

Shimoda K:
 Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan

Simhandl C:
 Bipolar Center Wiener Neustadt, Sigmund Freud University, Medical Faculty, Vienna, Austria

Slaney CM:
 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada

Squassina A:
 Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

Stamm T:
 Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany

 Department of Clinical Psychiatry and Psychotherapy, Brandenburg Medical School, Brandenburg, Germany

Stopkova P:
 National Institute of Mental Health, Klecany, Czechia

Maj M:
 Department of Psychiatry, University of Campania "Luigi Vanvitelli", Naples, Italy

Turecki G:
 Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada

Vieta E:
 Bipolar and Depressive Disorders Program, Institute of Neuroscience, Hospital Clínic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain

Veeh J:
 Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the Gothenburg University, Gothenburg, Sweden

Viswanath B:
 Department of Psychiatry, National Institute of Mental Health and Neuroscience, Bangalore, India

Witt SH:
 Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

Wright A:
 School of Psychiatry, University of New South Wales and Black Dog Institute, Sydney, New South Wales, Australia

Zandi PP:
 Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland

Mitchell PB:
 School of Psychiatry, University of New South Wales and Black Dog Institute, Sydney, New South Wales, Australia

Bauer M:
 Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany

Alda M:
 Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada

 National Institute of Mental Health, Klecany, Czechia

Rietschel M:
 Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

McMahon FJ:
 Intramural Research Program, National Institute of Mental Health, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland

Schulze TG:
 Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany

 Intramural Research Program, National Institute of Mental Health, National Institutes of Health, United States Department of Health and Human Services, Bethesda, Maryland

 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

 Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany

 Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, SUNY Upstate Medical University, Syracuse, New York

 Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August University Göttingen, Göttingen, Germany

Baune BT:
 Department of Psychiatry and Psychotherapy, University of Münster, Münster, Germany

 Department of Psychiatry, Melbourne Medical School, University of Melbourne, Parkville, Victoria, Australia

 Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia

Schubert KO:
 Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia

 Northern Adelaide Local Health Network, Mental Health Services, Adelaide, South Australia, Australia

Amare AT:
 Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia