Plasma-Assisted and Solvent-Free Ultra-Fast Synthesis of Gold and Gold Oxide Ultra-Small Nanoparticles and its use as Multi-Sensing Platforms.


Por: Sans J, Colombi S, Arnau M, Fontana-Escartín A, Resina L, García-Torres JM and Alemán C

Publicada: 1 dic 2025 Ahead of Print: 28 oct 2025
Resumen:
In this work, a plasma-assisted and solvent-free synthesis of gold (Au) and gold oxide (Au(2)O(3)) nanoparticles (NPs) is explored. Accordingly, only the precursor (i.e., HAuCl(4) powder) is exposed to the N(2):O(2) plasma gas mixtures, selected to promote its reduction to Au (HAuCl(4)-to-Au(0)) and/or favor its further oxidation to Au(2)O(3). As a result, the production of highly crystalline spherical Au ultra-small NPs (USNPs) of 2.7 ± 0.7 nm and Au(2)O(3) edged pyramidal-like NPs of 18 ± 5 nm is obtained in very short times (i.e., 10 s(-1) min), showing excellent stability without the need to add any ligands. To investigate the potential features of the synthesized particles, they are loaded into alginate hydrogels and tested as multi-detection sensor platforms of H(2)O(2) and NADH in front of several interferents. Although both samples present excellent electrochemical sensing activity (as compared to Au NPs synthesized through the Turkevich method), Au(2)O(3) NPs stand out for its high analytical sensibility toward H(2)O(2) (153.1 and 16.8 µA mm(-1) cm(-2) for single and multiplexing detection, simultaneously); and capacity to measure NADH in real human urine and low detection limits produced by Escherichia coli (7.5 × 10(3) CFU mL(-1)). Herein, a green, easy, and fast method is proposed to produce stable Au USNPs and Au(2)O(3) NPs, showing great potential for the catalytic and biomedical fields.

Filiaciones:
Sans J:
 Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Ed. I2, Barcelona, 08019, Spain

 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

 Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 10-12, Barcelona, 08028, Spain

Colombi S:
 Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Ed. I2, Barcelona, 08019, Spain

 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

Arnau M:
 Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Ed. I2, Barcelona, 08019, Spain

 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

Fontana-Escartín A:
 Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Ed. I2, Barcelona, 08019, Spain

 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

Resina L:
 Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Ed. I2, Barcelona, 08019, Spain

 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

García-Torres JM:
 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

 Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Engineering, Escola d'Enginyeria Barcelona Est (EEBE) and Institute for Research and Innovation in Health (IRIS), Universitat Politècnica de Catalunya (UPC), Barcelona, 08019, Spain

 CIBER en Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, Zaragoza, 50018, Spain

Alemán C:
 Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Ed. I2, Barcelona, 08019, Spain

 Barcelona Research Center in Multiscale Science and Engineering, Universitat Politècnica de Catalunya, C/ Eduard Maristany, 10-14, Barcelona, 08019, Spain

 Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 10-12, Barcelona, 08028, Spain
ISSN: 16136810





Small
Editorial
WILEY-V C H VERLAG GMBH, POSTFACH 101161, 69451 WEINHEIM, GERMANY, Alemania
Tipo de documento: Article
Volumen: 21 Número: 49
Páginas:
WOS Id: 001603531800001
ID de PubMed: 41147066
imagen Open Access

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