Serial lung ultrasounds in pediatric pneumonia in Mozambique and Pakistan
Por:
Ginsburg, AS, Nisar, I, Madrid, L, Lenahan, JL, Balouch, B, Vitorino, P, Hwang, J, Lamorte, A, Kanth, N, Bila, R, Valente, M, Varo, R, May, S, Bassat Q, Jehan, F and Volpicelli, G
Publicada:
18 mar 2021
Categoría:
Multidisciplinary
Resumen:
Lung ultrasound (LUS) is a promising point-of-care imaging technology for diagnosing and managing pneumonia. We sought to explore serial LUS examinations in children with chest-indrawing pneumonia in resource-constrained settings and compare their clinical and LUS imaging courses longitudinally. We conducted a prospective, observational study among children aged 2 through 23 months with World Health Organization Integrated Management of Childhood Illness chest-indrawing pneumonia and among children without fast breathing, chest indrawing or fever (no pneumonia cohort) at 2 district hospitals in Mozambique and Pakistan. We assessed serial LUS at enrollment, 2, 6, and 14 days, and performed a secondary analysis of enrolled children's longitudinal clinical and imaging courses. By Day 14, the majority of children with chest-indrawing pneumonia and consolidation on enrollment LUS showed improvement on follow-up LUS (100% in Mozambique, 85.4% in Pakistan) and were clinically cured (100% in Mozambique, 78.0% in Pakistan). In our cohort of children with chest-indrawing pneumonia, LUS imaging often reflected the clinical course; however, it is unclear how serial LUS would inform the routine management of non-severe chest-indrawing pneumonia.
Filiaciones:
Ginsburg, AS:
Univ Washington, Seattle, WA 98115 USA
Univ Washington, Clin Trial Ctr, Bldg 29,Suite 250,6200 NE 74th St, Seattle, WA 98115 USA
Nisar, I:
Aga Khan Univ, Dept Pediat & Child Hlth, Karachi, Pakistan
Madrid, L:
Univ Barcelona, Hosp Clin, ISGlobal, Barcelona, Spain
Lenahan, JL:
Save Children Federat Inc, Seattle, WA USA
Balouch, B:
Aga Khan Univ, Dept Pediat & Child Hlth, Karachi, Pakistan
Vitorino, P:
Ctr Invest Saude Manhica CISM, Maputo, Mozambique
Hwang, J:
Univ Washington, Seattle, WA 98115 USA
Lamorte, A:
Parini Hosp, Dept Emergency Med, Aosta, Italy
Kanth, N:
Sindh Govt Childrens Hosp Poverty Eradicat Initia, Karachi, Pakistan
Bila, R:
Ctr Invest Saude Manhica CISM, Maputo, Mozambique
Valente, M:
Univ Barcelona, Hosp Clin, ISGlobal, Barcelona, Spain
:
Univ Barcelona, Hosp Clin, ISGlobal, Barcelona, Spain
May, S:
Univ Washington, Seattle, WA 98115 USA
Bassat Q:
Univ Barcelona, Hosp Clin, ISGlobal, Barcelona, Spain
Jehan, F:
Aga Khan Univ, Dept Pediat & Child Hlth, Karachi, Pakistan
Volpicelli, G:
San Luigi Gonzaga Univ Hosp, Dept Emergency Med, Orbassano, Italy
Green Submitted, gold
|