VACCINE FAILURES IN PATIENTS PROPERLY VACCINATED WITH 13-VALENT PNEUMOCOCCAL CONJUGATE VACCINE IN CATALONIA, A REGION WITH LOW VACCINATION COVERAGE
Por:
Moraga-Llop F, García-García JJ, Díaz-Conradi A, Ciruela Navas P, Martínez J, González S, Hernández S, Fernández de Sevilla-Estrach M, Uriona S, Izquierdo C, Selva L, Campins M, Codina MG, Batalla J, Esteva-Afonso C, Domínguez À and Munoz-Almagro C
Publicada:
1 abr 2016
Ahead of Print:
11 dic 2015
Resumen:
Vaccine failures occurring with 13-valent pneumococcal conjugate vaccine
(PCV13) in 3 pediatric hospitals in Barcelona (2012-2013) are described.
PCV13 vaccine failure was defined as the occurrence of an invasive
pneumococcal infection in children properly vaccinated by PCV13. Among
84 patients with invasive pneumococcal infection, 32 had received at
least one dose of PCV13. Seventeen of them had invasive pneumococcal
infection produced by a PCV13 serotype. Among those, 9 patients were
considered to have a PCV13 vaccine failure. Serotype 3 was isolated in 6
patients, serotype 19A in 2 and serotype 6B in 1.
Filiaciones:
Moraga-Llop F:
1Pediatrics, Hospital Vall d'Hebron, BARCELONA, Spain. 2Pediatrics, Hospital Sant Joan de Déu, BARCELONA, Spain. 3Pediatrics, Hospital de Nens, BARCELONA, Spain. 4Agència de Salut Pública de Catalunya, Departament de Salut, BARCELONA, Spain. 5Microbiology, Hospital Vall d'Hebron, BARCELONA, Spain. 6Preventive Medicine, Hospital Vall d'Hebron, BARCELONA, Spain. 7CIBER Epidemiología y Salud Pública (CIBERESP), MADRID, Spain. 8Microbiology, Hospital Sant Joan de Déu, BARCELONA, Spain. 9Departament
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