Cross-national clinical and functional remission rates: Worldwide Schizophrenia Outpatient Health Outcomes (W-SOHO) study
Por:
Haro JM, Novick D, Bertsch J, Karagianis J, Dossenbach M and Jones PB
Publicada:
1 sep 2011
Resumen:
Background
Evidence suggests that schizophrenia may have a better outcome for
individuals living in low- and middle-income countries compared with
affluent settings.
Aims
To determine the frequency of symptom and functional remission in
out-patients with schizophrenia in different regions of the world.
Method
Using data from the Worldwide-Schizophrenia Outpatient Health Outcomes
(W-SOHO) study we measured clinical and functional remission in
out-patients with schizophrenia in different regions of the world, and
examined sociodemographic and clinical factors associated with these
outcomes. The 11 078 participants analysed from 37 participating
countries were grouped into 6 regions: South Europe, North Europe,
Central and Eastern Europe, Latin America, North Africa and Middle East,
and East Asia.
Results
In total, 66.1% achieved clinical remission during the 3-year follow-up
(range: 60.1% in North Europe to 84.4% in East Asia) and 25.4%
achieved functional remission (range: 17.8% in North Africa and Middle
East to 35.0% in North Europe). Regional differences were not explained
by participants' clinical characteristics. Baseline social functioning,
being female and previously untreated were consistent predictors of
remission across regions.
Conclusions
Clinical outcomes of schizophrenia seem to be worse in Europe compared
with other regions. However, functional remission follows a different
pattern.
Open Access
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